CA · West
San Francisco Bay Area venture capital & startups
Bay Area frontier AI and enterprise platforms — still the US venture center of gravity.
The Bay Area remains the deepest pool of multi-stage capital for AI, consumer internet, and infrastructure. Pair our SF hubs with national fund profiles.
Funds matched by headquarters aliases; startups by hq field plus curated IDs when verified.
Venture firms in San Francisco Bay Area
Matched from fund headquarters in our directory (alias-based). Dual-HQ firms may appear in more than one city.
| Firm | HQ (directory) | Leads |
|---|---|---|
| Cowboy Ventures | New York, NY & Palo Alto, CA | Pre-Seed, Seed |
| Forerunner Ventures | New York, NY & San Francisco, CA | Seed, Series A |
| Ribbit Capital | New York, NY & Palo Alto, CA | Series A, Series B+ |
| 01 Advisors | San Francisco, CA | Series A, Series B+ |
| Afore Capital | San Francisco, CA | Pre-Seed, Seed |
| AI Fund | Palo Alto, CA | Seed |
| Alpaca VC | San Francisco, CA | Seed, Series A, Series B+ |
| Altimeter Capital | Menlo Park, CA | Series B+ |
| Andreessen Horowitz | Menlo Park, CA | Series A, Series B+ |
| Base10 Partners | San Francisco, CA | Seed, Series A |
| Benchmark | San Francisco, CA | Series A |
| Cantos | San Francisco, CA | Pre-Seed, Seed |
| Craft Ventures | San Francisco, CA | Seed, Series A |
| Define Ventures | San Francisco, CA | Series A |
| First Round | San Francisco, CA | Pre-Seed, Seed |
| Floodgate | Palo Alto, CA | Pre-Seed, Seed |
| Fusion Fund | Palo Alto, CA | Seed, Series A |
| Greylock | Menlo Park, CA | Seed, Series A |
| IndieBio | San Francisco, CA | Pre-Seed, Seed |
| Initialized Capital | San Francisco, CA | Seed, Series A |
| Khosla Ventures | Menlo Park, CA | Seed, Series A |
| Kleiner Perkins | Menlo Park, CA | Series A, Series B+ |
| Menlo Ventures | Menlo Park, CA | Series A, Series B+ |
| Neo | San Francisco, CA | Pre-Seed, Seed |
| Norwest Venture Partners | Palo Alto, CA | Series A, Series B+ |
| Pear VC | Menlo Park, CA | Pre-Seed, Seed |
| Scale Venture Partners | Foster City, CA | Series A, Series B+ |
| Sequoia Capital | Menlo Park, CA | Seed, Series A, Series B+ |
| Slow Ventures | San Francisco, CA | Seed, Series A |
| Susa Ventures | San Francisco, CA | Seed |
Startups we cover in San Francisco Bay Area
Matched from startup hq fields. Many profiles still lack HQ — curated lists in editorial notes fill gaps when verified.
| Startup | One-liner | HQ |
|---|---|---|
| 11x | AI digital workers for revenue teams — autonomous SDR Alice and voice agent Jordan. | San Francisco, CA |
| Abridge | AI medical scribe capturing clinician-patient conversations into structured EHR notes. | San Francisco, California |
| Aerodome | Drone-as-first-responder platform for police — automated aerial response to 911 calls. | San Francisco, California |
| AgentMail | API-first email inboxes built for autonomous AI agents. | San Francisco, CA |
| Airbnb | Global marketplace connecting guests with short-term stays and experiences. | San Francisco, California |
| AKASA | Generative AI platform automating healthcare revenue cycle operations. | South San Francisco, California |
| Amber | RNA-based multi-kilobase gene editing platform for diseases with high allelic diversity. | San Francisco, California |
| Ambience | Ambient AI platform for clinical documentation, medical coding, and health-system workflows. | San Francisco, California |
| Ambience Healthcare | Ambient AI platform for clinical documentation, coding, and health-system workflows. | San Francisco, California |
| Ambient.ai | Computer-vision intelligence platform for enterprise physical security. | Menlo Park, California |
| Amiato | NoSQL-to-warehouse data migration for cloud analytics; acquired by AWS in 2014. | Palo Alto, California |
| Amplitude | Product analytics and behavioral data platform for digital teams. | San Francisco, California |
| Anchorage | Regulated crypto custody and banking platform for institutions (Anchorage Digital). | San Francisco, California |
| Angle | Decentralized over-collateralized stablecoin protocol (EURA and USDA). | San Francisco, CA |
| Anthropic | AI safety company building Claude frontier models, API, and enterprise agents for coding and knowledge work. | San Francisco, California |
| AnyRoad | Experience relationship management platform for brand activations and events. | San Francisco, CA |
| Anyscale | Commercial platform for Ray distributed computing — scale AI/ML workloads on any cloud. | San Francisco, California |
| Apollo | GraphQL platform (Apollo GraphOS) for unified API development at enterprise scale. | San Francisco, California |
| Aptos | High-throughput layer-1 blockchain built on the Move programming language. | Palo Alto, California |
| Aradigm | Benefits platform enabling sustainable employer access to cell and gene therapies. | San Francisco, California |
| Arda Therapeutics | Targeted cell-depletion therapies for chronic diseases using oncology modalities outside cancer. | South San Francisco, California |
| Arena | AI evaluation platform behind Chatbot Arena / LMArena leaderboards. | San Francisco, California |
| Arimo | Behavioral AI and predictive analytics for IoT and enterprise data (formerly Adatao). | Redwood City, California |
| Armada | Modular edge AI data centers and full-stack edge computing platform. | San Francisco, CA |
| Asana | Work management and team collaboration software. | San Francisco, California |
| Asserts | Contextual observability intelligence for Prometheus and OpenTelemetry metrics. | San Francisco, CA |
| Asserts.ai | Observability contextual intelligence for Prometheus/OpenTelemetry (acquired by Grafana). | San Francisco, CA |
| Astranis | Small geostationary satellites delivering dedicated regional broadband connectivity. | San Francisco, California |
| Astro Mechanica | Supersonic turboelectric adaptive jet engine and aircraft developer. | San Francisco, California |
| Atlys | Digital visa application platform for international travelers. | San Francisco, California |
| Authy | Two-factor authentication API for developers and enterprises. | San Francisco, CA |
| Automatic | OBD-II connected car adapters and apps for diagnostics, safety, and usage-based insurance. | San Francisco, California |
| Barefoot Networks | Programmable Ethernet switch ASICs and P4 networking software for data centers. | Santa Clara, California |
| Baseten | AI inference platform for deploying, serving, and autoscaling production models with OpenAI-compatible APIs. | San Francisco, California |
| BBA Inc | Meldium — team SSO and cloud app password management, acquired by LogMeIn in 2014. | San Francisco, California |
| Beacons | Creator business platform for link-in-bio sites, storefronts, and audience monetization. | San Francisco, CA |
| Bedrock Robotics | Retrofit autonomy kit turning 20–80 ton excavators into supervised self-driving earthmovers on construction sites. | San Francisco, California |
| Belong | Residential rental marketplace replacing landlord–tenant friction with homeowner–resident relationships. | San Francisco, California |
| Benchling | R&D cloud platform — the operating system for life science labs. | San Francisco, California |
| BigScreen | Social VR platform and Bigscreen Beyond micro-OLED headset hardware. | San Francisco, CA |
| Black Ore Technologies | AI platform automating tax prep and financial-services workflows (Tax Autopilot). | San Francisco, California |
| Blend Labs | Digital lending platform for mortgages and consumer banking (NYSE: BLND). | San Francisco, California |
| Bounce | Global luggage storage marketplace for travelers. | San Francisco, California |
| Box | Cloud content management and collaboration for enterprises (NYSE: BOX). | Redwood City, California |
| Bracket Computing | Enterprise 'Computing Cell' software for secure multi-cloud workload portability. | Mountain View, California |
| Braid.ai | Creator-economy analytics and direct-to-fan tools (Braid.ai). | San Francisco, California |
| Braintrust | AI evaluation, observability, and prompt tooling for production LLM products. | San Francisco, California |
| Branch | Mobile deep-linking and attribution infrastructure (Branch.io). | Palo Alto, California |
| Branch International | Mobile-first lending and financial services for emerging markets (Branch.co). | San Francisco, California |
| Brex | Corporate card and spend management for high-growth companies. | San Francisco, California |
| Bromium | Micro-virtualization endpoint security isolating browser and app threats. | Cupertino, California |
| BuildZoom | Data-driven marketplace matching homeowners with licensed contractors. | San Francisco, California |
| Bump Technologies | Mobile app for tap-to-share contacts, photos, and files between phones. | Mountain View, California |
| Cape | Privacy-first mobile carrier with identifier rotation and secondary numbers. | San Francisco, California |
| Capriza | Enterprise mobility platform that auto-converts web apps to mobile (legacy). | Palo Alto, California |
| Carta | Equity management and cap table platform for private companies and funds. | San Francisco, California |
| Cartography Biosciences | Oncology biotech building an antigen atlas for precise antibody immunotherapies. | South San Francisco, California |
| Casa | Subscription home management platform — digital twin plus concierge for single-family homeowners. | San Francisco, California |
| Celo | Mobile-first blockchain for payments and stablecoins in emerging markets. | San Francisco, CA |
| Census | Reverse ETL platform syncing warehouse-modeled data into CRMs, ad tools, and other business apps. | San Francisco, California |
| Cerebras | Wafer-scale AI chips and inference cloud — CS-3 systems and Cerebras Inference API for training and production LLM serving. | Sunnyvale, CA |
| Chia | Proof-of-space-and-time blockchain (Chia Network) designed for lower-energy crypto mining. | South San Francisco, California |
| ClearStory Data | Data harmonization and visual analytics platform blending internal and third-party datasets. | Menlo Park, California |
| Clerk | Drop-in authentication, user management, and session handling for web and mobile apps. | San Francisco, California |
| Clipboard | Web clipping and social bookmarking service for saving rich web snippets (Clipboard.com). | San Francisco, California |
| Clubhouse | Social audio app for live voice rooms, creator conversations, and drop-in networking. | San Francisco, California |
| Cluely | AI desktop assistant delivering real-time coaching and answers during meetings and sales calls. | San Francisco, California |
| Coactive | Multimodal AI platform to search, label, and analyze enterprise image and video data. | San Francisco, California |
| Coactive AI | Multimodal AI platform to search, label, and analyze enterprise image and video data. | San Francisco, California |
| CodeCombat | Game-based platform teaching kids computer science and coding. | San Francisco, CA |
| Codi | Flexible private office platform with turnkey workplace management for hybrid teams. | San Francisco, California |
| Cognition | Autonomous AI software engineer Devin — agents that code, debug, and ship production software for enterprises. | San Francisco, CA |
| Command Zero | AI agents that automate SOC investigations — alert triage to analyst-ready reports. | San Francisco, California |
| Compound | Ethereum lending protocol — algorithmic money markets with COMP governance token. | San Francisco, California |
| Concourse | Enterprise AI agents connected to ERPs and finance systems for corporate teams. | San Francisco, California |
| Convex | Reactive TypeScript backend — database, serverless functions, and real-time sync in one platform. | San Francisco, California |
| Corgi Insurance | AI-native full-stack commercial insurer for startups — direct underwriting, claims, and embedded distribution. | San Francisco, CA |
| Cowboy Space Corporation | Orbital infrastructure — space-based power transmission and data centers (ex-Aetherflux). | San Francisco, California |
| Cresta | Real-time AI coaching and automation for contact center agents. | Palo Alto, California |
| Cumulus Networks | Linux-based open networking OS for data center switches (acquired by NVIDIA, 2020). | Mountain View, California |
| CYGNVS | Crisis operating system for out-of-band cyber incident response. | San Francisco, CA |
| Cyngn | Industrial autonomy company (NASDAQ: CYN) retrofitting forklifts with DriveMod AI. | Menlo Park, CA |
| Decagon | Enterprise AI agents automating customer support across chat, voice, and ops. | San Francisco, California |
| DeepInfra | Managed AI inference cloud — OpenAI-compatible API for 190+ open models at production scale. | Palo Alto, CA |
| Delphix | Database virtualization and test data management (acquired by Perforce, 2024). | Redwood City, California |
| depthfirst | Applied AI lab building security-specific models and autonomous remediation (General Security Intelligence). | San Francisco, CA |
| Descript | AI-powered audio and video editor — edit media like a text document. | San Francisco, California |
| DeSO | Layer-1 blockchain for decentralized social apps (ex-BitClout). | San Francisco, California |
| Dialpad | AI-native unified communications and contact center platform (UCaaS + CCaaS). | San Francisco, California |
| Diode | AI software automating PCB schematic design for U.S. circuit-board manufacturing. | San Francisco, California |
| Dispatch | Sidewalk delivery-robot startup acquired by Amazon for Scout program. | San Francisco, CA |
| Divvy Homes | Rent-to-own housing platform — renters build equity toward homeownership. | San Francisco, California |
| DoNotPay | Consumer legal-automation app — 'robot lawyer' for parking tickets, subscriptions, bureaucracy. | San Francisco, California |
| DoorDash | U.S. delivery logistics platform — public on NYSE as DASH since December 2020. | San Francisco, California |
| Doppel | AI-native platform detecting and removing social-engineering impersonation and phishing. | San Francisco, California |
| Doxel | Computer-vision construction progress tracking — robots and drones vs. BIM plans. | Menlo Park, California |
| dYdX | Decentralized perpetuals exchange on dYdX Chain appchain. | San Francisco, California |
| Earli | Synthetic biopsy biotech — forces tumors to produce detectable biomarkers for early cancer localization. | South San Francisco, California |
| Earn.com | Paid email and micropayments platform (formerly 21.co) — acquired by Coinbase, 2018. | San Francisco, California |
| Earnin | Earned wage access app — cash out paychecks early without mandatory fees or payday loans. | Palo Alto, California |
| Entropy | Decentralized crypto custody startup — shut down and returned capital (Jan 2026). | San Francisco, California |
| fal | Real-time generative media inference APIs for image, video, audio, and 3D at scale. | San Francisco, California |
| Fei Protocol | Algorithmic USD stablecoin protocol that merged with Rari Capital — both wound down after 2022 exploits. | San Francisco, California |
| Forta Network | Decentralized real-time monitoring network detecting threats and anomalies on blockchain transactions. | San Francisco, California |
| Forward Networks | Network assurance platform that models enterprise networks as searchable digital twins for verification and troubleshooting. | Santa Clara, California |
| Freatic | On-chain information markets protocol for decentralized prediction and data feeds. | San Francisco, California |
| FurtherAI | Insurance-native AI workspace automating submissions, underwriting audits, claims intake, and policy comparisons. | San Francisco, California |
| Gainspeed | Virtual CCAP and distributed access software for cable operators—acquired by Nokia 2016. | Sunnyvale, California |
| Gamma.app | AI-native platform for creating presentations, documents, and visual storytelling. | San Francisco, California |
| Genesis Molecular AI | AI-first drug discovery company using generative models for small-molecule design. | Burlingame, California |
| GitHub | Developer platform for hosting, reviewing, and collaborating on code — acquired by Microsoft in 2018. | San Francisco, California |
| Glow | Women's health and fertility-tracking app founded by Max Levchin. | San Francisco, California |
| Gobble | 15-minute dinner meal-kit delivery for busy families—acquired by Intelligent Foods in 2022, still operating. | San Francisco, California |
| Golden | Self-constructing knowledge graph for research—acquired by ComplyAdvantage in 2024. | San Francisco, California |
| GoodData | Cloud analytics and business-intelligence platform for enterprise data products. | San Francisco, California |
| Granular | Farm-management software for large commercial growers (acquired by Corteva). | San Francisco, California |
| Gusto | Payroll, benefits, and HR platform for small businesses. | San Francisco, California |
| Halliday | Agentic Workflow Protocol for Web3 — automate onchain payments and treasury flows without per-use-case smart contracts. | San Francisco, California |
| Hark | Brett Adcock's AI lab building multimodal personal intelligence plus purpose-built hardware devices. | San Jose, California |
| Harvey | Domain-specific AI for law firms — research, drafting, contract analysis, and agentic legal workflows. | San Francisco, California |
| Helix | Population genomics and clinical-research platform spun out of Illumina — consumer DNA marketplace. | San Mateo, California |
| Hex | Collaborative analytics notebook combining SQL, Python, R, and no-code into shareable data apps. | San Francisco, California |
| Hilbert | Agentic AI growth infrastructure for B2C brands—data labeling, analytics, and automated execution. | San Francisco, California |
| Hilbert's AI | Alias for Hilbert — AI-native B2C growth infrastructure with agentic analytics at hilberts.ai. | San Francisco, California |
| Hipcamp | Marketplace unlocking private land for camping, glamping, and RV stays. | San Francisco, California |
| Hippocratic AI | Healthcare LLM company focused on safety-tuned models for patient-facing clinical workflows. | Palo Alto, California |
| Honor | Tech-enabled home care network matching professional caregivers with seniors — merged with Home Instead. | San Francisco, California |
| Human Archive | Multimodal training-data infrastructure for physical AI — egocentric video, tactile, and mocap from India's gig workforce. | San Francisco, California |
| iCracked | On-demand smartphone and tablet repair network—acquired by Allstate/SquareTrade in 2019. | San Francisco, California |
| IFTTT | Automation platform connecting 700+ apps and devices through 'if this, then that' applets. | San Francisco, California |
| Illumio | Zero-trust microsegmentation platform for data-center and cloud breach containment. | Sunnyvale, California |
| Imgur | Community image and GIF hosting—bootstrapped five years before a16z-led $40M Series A. | San Francisco, California |
| Imply | Commercial Apache Druid company — real-time analytics database for operational and product analytics. | Burlingame, California |
| Inceptive | AI-designed mRNA molecules licensed to pharma—founded by Transformer co-author Jakob Uszkoreit. | Palo Alto, California |
| Incredible Health | Permanent healthcare hiring marketplace — matches nurses to health systems with AI screening. | San Francisco, California |
| Inferact | Company behind vLLM — open-source LLM inference engine used by Meta, Google, and Character.ai in production. | San Francisco, California |
| Infinitus | AI voice agents that automate payer phone calls for benefit verification and prior authorization. | San Francisco, California, USA |
| Inngest | Durable step-function platform for serverless workflows and AI agent orchestration. | San Francisco, California, USA |
| Insitro | ML-driven drug discovery platform applying large-scale biology data to identify novel therapeutics. | South San Francisco, California |
| Instabase | Applied AI platform for enterprise unstructured document processing and workflow automation. | San Francisco, California |
| Instacart | Grocery delivery marketplace connecting consumers, retailers, and personal shoppers. | San Francisco, California |
| Mobile photo-sharing app with filters and social graph — acquired by Facebook for ~$1B in 2012. | Menlo Park, California | |
| Instart | Endpoint-aware CDN and application delivery platform — acquired by Akamai in 2020. | Palo Alto, California |
| Intrinsic | Alphabet/Google robotics software — Flowstate platform makes industrial robots easier to program with AI and simulation. | Mountain View, California |
| Iron Fish | Privacy-focused Layer 1 blockchain using zk-SNARKs for shielded transactions. | San Francisco, California |
| Isara Laboratories | San Francisco startup building infrastructure for coordinating thousands of AI agents on complex analytical tasks. | San Francisco, California |
| Isovalent | Creators of Cilium and Tetragon eBPF networking — acquired by Cisco in April 2024. | Cupertino, California |
| Jarvie AI | Agentic AI assistant embedded in iMessage group chats for coordination and tasks. | San Francisco, California |
| Jeeves | Global corporate cards and expense management for startups operating across borders. | San Francisco, California |
| Jungla | ML platform for clinical genetic variant interpretation—acquired by Invitae in 2019. | San Francisco, California |
| k-ID | Global compliance engine for age-appropriate gaming and youth online safety. | San Francisco, California |
| Kaedim | AI 2D-to-3D asset generation with human-in-the-loop for game studios and brands. | San Francisco, California |
| Kairos | Trading terminal and analytics for prediction markets including Kalshi and Polymarket. | San Francisco, California |
| Keep Financial | Vesting cash bonus platform—upfront employee payments that forgive as workers stay. | San Jose, California |
| Keep Network | Decentralized tBTC bridge — merged with NuCypher to form Threshold Network. | San Francisco, California |
| Keycard | Identity and access management platform purpose-built for AI agents in enterprises. | San Francisco, California |
| Kindred | Members-only home-swapping network for affordable travel. | San Francisco, California |
| Kinter | Agentic AI accountants automating expense-side accounting close inside ERPs. | San Francisco, California |
| Kiosk | Farcaster social client integrating onchain assets into community commerce. | San Francisco, California |
| Kno | Digital textbook and study platform — acquired by Intel in 2013. | Santa Clara, California |
| Knowmia | Curated K-12 educational video discovery for teachers—acquired by TechSmith in 2014. | San Francisco, California |
| KoBold Metals | AI-driven mineral exploration for battery metals — copper, cobalt, nickel, lithium. | Berkeley, California |
| Kodex | SaaS for verifying and responding to government and law-enforcement data requests. | San Francisco, California |
| Kong | Cloud API gateway and connectivity platform built on open-source Kong. | San Francisco, California |
| Krea | Unified GenAI creative platform for real-time image and video generation. | San Francisco, California |
| Labelbox | Training data platform for ML teams — labeling, curation, and model evaluation. | San Francisco, California |
| Larridin | AI execution intelligence platform measuring enterprise AI adoption, shadow AI, and ROI. | San Francisco, California |
| Lassie | AI agents that automate small-business back offices—starting with dental and medical practices. | San Francisco, California |
| Latent Health | Clinical AI platform accelerating medication access via prior auth and pharmacy workflows. | San Francisco, CA |
| Lightup | No-code data quality monitoring for enterprise data pipelines and warehouses. | San Francisco, California |
| Lime | Shared electric scooters and bikes for urban micromobility in 50+ cities. | San Francisco, California |
| Limitless | AI wearable pendant for personal memory — formerly Rewind desktop capture; acquired by Meta 2025. | San Francisco, California |
| Lob.com | API for programmatic direct mail — print, ship, and verify addresses at scale. | San Francisco, California |
| Local Motion | Enterprise fleet-sharing hardware and software for corporate campuses—acquired by Zipcar in 2015. | San Francisco, California |
| Locale | Curated high-protein meal delivery — organic ingredients, no seed oils, longevity-nutrition standards. | San Francisco, California |
| Lookout | Mobile security platform — malware protection, app risk, and enterprise mobile threat defense. | San Francisco, California |
| Loom | Async video messaging for workplace communication — acquired by Atlassian for $975M. | San Francisco, California |
| Lowkey | Game clip capture and highlights for streamers—team acquired by Niantic in 2021. | San Francisco, California |
| LTSE | SEC-registered stock exchange and software for long-term company governance. | San Francisco, California |
| Luma AI | Multimodal generative AI — Dream Machine text-to-video and 3D capture. | Palo Alto, California |
| Lumos | SaaS identity governance — app access reviews, shadow IT discovery, and automated provisioning. | San Francisco, California |
| Lyft | Ridesharing platform — second-largest US ride-hail network, public since 2019. | San Francisco, California |
| Lytro | Light-field cameras with post-capture refocus—pivoted to cinema VR, shut down March 2018. | Mountain View, California |
| Macro | AI-native document workspace — PDFs, slides, and knowledge-worker productivity reimagined. | San Francisco, California |
| Mana Bio | AI-native biotech designing lipid nanoparticles for targeted RNA and gene-therapy delivery beyond the liver. | San Francisco, California |
| Massive Health | Built The Eatery, a photo food-journal app for wellness—team acquired by Jawbone in 2013. | San Francisco, California |
| Material Security | Cloud email security — account takeover protection and data loss prevention for Google and Microsoft. | San Francisco, California |
| Matik | Automates personalized, data-driven sales and customer-success presentations from CRM and warehouse data. | San Francisco, California |
| Mayvenn | Beauty-tech marketplace — stylists sell hair products via inventory-free e-commerce storefronts. | Oakland, California |
| Maze Therapeutics | Clinical-stage biotech using human genetics to develop precision small-molecule medicines. | South San Francisco, California |
| Medium | Online publishing platform for long-form writing, blogs, and member-supported newsletters. | San Francisco, California |
| Mem | AI-native note-taking with self-organizing knowledge graph and team collaboration. | San Francisco, California |
| Memora Health | AI care navigation via SMS and phone for complex patients—acquired by Commure in 2024. | San Francisco, California |
| Mercury | Startup banking — checking, treasury, cards, and financial workflows for tech companies. | San Francisco, California |
| Merkle Manufactory, Inc. | Developer of Farcaster, a decentralized social protocol with onchain identities and client apps. | San Francisco, CA |
| Mesosphere | Enterprise Kubernetes and DC/OS platform (rebranded D2iQ; assets acquired by Nutanix). | San Francisco, CA |
| Metatheory | Web3 gaming studio building on-chain franchises, founded by Twitch co-founder Kevin Lin. | San Francisco, CA |
| Midstream Health | AI financial action platform for healthcare systems' spend and revenue operations. | Oakland, CA |
| Mind Robotics | AI-powered industrial robotics platform founded by Rivian CEO RJ Scaringe. | Palo Alto, CA |
| Mintlify | AI-powered developer documentation platform for API and product docs. | San Francisco, CA |
| Mixpanel | Product analytics platform for event-based user behavior and funnel analysis. | San Francisco, CA |
| Morta Security | Advanced threat detection from former NSA engineers—acquired by Palo Alto Networks in 2014. | Redwood City, California |
| Mosaic | Construction technology platform for precision-built homes with local homebuilder partners. | San Francisco, CA |
| Mother Computer Inc. | Open-source local AI hardware and software for on-device model inference. | Mountain View, CA |
| Mountaintop Studios | Game studio founded by Oculus co-founder Nate Mitchell building competitive PvP titles. | San Francisco, CA |
| Mux | Developer API platform for video streaming, encoding, and playback analytics. | San Francisco, CA |
| Mysten Labs | Builders of the Sui blockchain — high-throughput L1 from ex-Meta Diem engineers. | Palo Alto, CA |
| Nash | API platform orchestrating last-mile delivery across carriers for retailers. | San Francisco, CA |
| Navan | Corporate travel and expense management platform (formerly TripActions). | Palo Alto, CA |
| NEAR | Layer-1 blockchain for scalable dApps with sharded proof-of-stake. | San Francisco, CA |
| Netlify | Web development platform for Jamstack and modern frontend deployment. | San Francisco, CA |
| Nicira Networks | Software-defined networking pioneer (OpenFlow/NVP)—acquired by VMware for $1.26B in 2012. | Palo Alto, California |
| Notion | All-in-one workspace for docs, wikis, databases, and AI-assisted knowledge work. | San Francisco, CA |
| Nova Labs | Company behind Helium — decentralized wireless networks for IoT and 5G. | San Francisco, CA |
| Oasis Labs | Privacy-first blockchain and confidential compute platform founded by UC Berkeley professor Dawn Song. | San Francisco, California, USA |
| Oculus VR | Kickstarter VR headset maker—acquired by Facebook (Meta) for ~$2B in 2014. | Menlo Park, California |
| Okta | Enterprise identity and access management — SSO, MFA, and workforce identity cloud. | San Francisco, California, USA |
| Omada Health | Virtual chronic-care programs for diabetes, hypertension, musculoskeletal, and behavioral health. | San Francisco, California, USA |
| OpenAI | Frontier AI lab behind ChatGPT, GPT models, and API platform for developers and enterprises. | San Francisco, California, USA |
| Opendoor | iBuying pioneer—instant online home offers; public via SPAC December 2020 (NASDAQ: OPEN). | San Francisco, California |
| OpenGov | Cloud ERP, budgeting, and permitting software for U.S. cities, counties, and state agencies. | San Jose, California, USA |
| OpenInvest | ESG direct-indexing platform for wealth advisors before J.P. Morgan acquired it in 2021. | San Francisco, CA |
| Optimizely | Enterprise A/B testing and experimentation platform; acquired by Episerver in 2020, now the combined company brand. | San Francisco, CA |
| Orchestra Bio | Agentic R&D operations platform unifying scientific, financial, and operational planning for biotechs. | San Francisco, California, USA |
| Orchid Labs | Decentralized VPN protocol using blockchain tokens to route traffic around censorship. | San Francisco, CA |
| Orderful | AI-native EDI platform replacing manual B2B supply-chain data integrations. | San Francisco, CA |
| Otter.ai | AI meeting assistant for real-time transcription, summaries, and collaborative notes. | Mountain View, California, USA |
| PagerDuty | Incident management platform for on-call alerting and response. | San Francisco, California, USA |
| Palmstreet | Live-shopping marketplace for rare plants, crafts, and collector goods. | Menlo Park, CA |
| Paloma | AI-native CRM stitching contracts, usage, and invoices for post-sales revenue teams. | San Francisco, CA |
| Patch | API-first carbon removal marketplace embedding climate offsets into business workflows. | San Francisco, CA |
| Pave | Real-time compensation benchmarking and merit-cycle planning for startups. | San Francisco, CA |
| People.ai | Revenue operations platform using AI to automate CRM data capture from sales activity. | San Francisco, California, USA |
| Periodic Labs | AI-native autonomous lab accelerating materials science via robotic experimentation. | San Francisco, CA |
| Petual | Agentic AI platform automating internal audit and SOX compliance testing. | San Francisco, CA |
| Phantom | Crypto wallet for Solana, Ethereum, and multichain DeFi and NFTs. | San Francisco, California, USA |
| Phylo | Agentic AI lab building an integrated biology environment (IBE) for biomedical research. | South San Francisco, CA |
| PiCloud | Python PaaS for parallel cloud computing — acqui-hired by Dropbox in 2013. | Sunnyvale, CA |
| Visual discovery and bookmarking platform for ideas, shopping, and planning. | San Francisco, California, USA | |
| Pixate | YC S12 mobile prototyping tool with CSS-styled native interactions — acquired by Google in 2015. | San Francisco, CA |
| Plaid | Financial data network connecting apps to users' bank accounts via APIs. | San Francisco, California, USA |
| PlanetScale | Serverless MySQL-compatible database platform with branching and Vitess scaling. | San Francisco, California, USA |
| Point | Home equity investments — cash today for a share of future home appreciation, not debt. | Palo Alto, CA |
| Polychain | Crypto-native hedge and venture firm founded by ex-Coinbase employee Olaf Carlson-Wee. | San Francisco, CA |
| Poseidon | Decentralized data layer licensing AI training data via Story Protocol smart contracts. | San Francisco, CA |
| Preset | Managed cloud platform for Apache Superset open-source business intelligence. | San Mateo, CA |
| Prisms | VR spatial-learning platform for K-12 math and STEM education. | San Francisco, CA |
| Product Hunt | Daily community leaderboard where makers launch and discover new tech products. | San Francisco, CA |
| Prometheus | Physical-AI company building an "artificial general engineer" to automate design and manufacturing of complex hardware. | San Francisco, California, USA |
| Promise | Flexible, interest-free payment plans for government and utility bills. | Oakland, CA |
| Promptfoo | Open-source LLM evaluation and red-teaming toolkit for enterprise AI safety. | San Francisco, California, USA |
| Proof of Play | On-chain game studio behind Pirate Nation, founded by FarmVille co-creator. | San Francisco, California, USA |
| Protocol Labs | Research and development company behind IPFS, Filecoin, and libp2p decentralized web protocols. | San Francisco, California, USA |
| Proven.com | Mobile hiring app for small businesses — acquired by Upward in 2019. | San Francisco, CA |
| Pylon | Agentic B2B customer-support platform unifying Slack, Teams, email, and AI agents. | San Francisco, CA |
| Quora | Q&A platform; Poe is a multi-model AI chat and bot-creation marketplace. | Mountain View, CA |
| Red Hot Labs | Mobile social game studio acquired by Google in 2012. | San Francisco, CA |
| Community forum platform organized by subreddits with voting and AMA culture. | San Francisco, California, USA | |
| Reducto | AI document-intelligence platform parsing PDFs and unstructured files for enterprise agents. | San Francisco, CA |
| Reflektive | Real-time performance feedback platform acquired by Cornerstone OnDemand. | San Francisco, CA |
| Reforge | Professional education platform for growth, product, and marketing leaders. | San Francisco, California, USA |
| Regrello | AI workflow automation for manufacturing supply chains, acquired by Salesforce in 2025. | San Francisco Bay Area, CA |
| Replicate | Cloud platform to run and deploy open-source ML models via API. | San Francisco, California, USA |
| Replit | Browser-based IDE and AI agent platform for building and deploying apps. | San Francisco, California, USA |
| Rescale | High-performance computing cloud for engineering simulation and AI workloads. | San Francisco, California, USA |
| Resend | Email API for developers with modern DX and React Email integration. | San Francisco, California, USA |
| Rezo Therapeutics | Biotech mapping disease networks from UCSF QBI tech for precision therapeutics. | San Francisco Bay Area, CA |
| Rigetti | Superconducting quantum processors; public via SPAC on NASDAQ (RGTI). | Berkeley, CA |
| Rippling | Workforce platform unifying HR, IT, payroll, and corporate spend. | San Francisco, California, USA |
| Robinhood | Commission-free mobile brokerage for stocks, options, crypto, and cash management. | Menlo Park, California, USA |
| Roblox | User-generated gaming platform and virtual economy for immersive experiences. | San Mateo, California, USA |
| Rockmelt | Social web browser acquired by Yahoo in 2013 for roughly $60–70M. | Mountain View, CA |
| Roebling | AI-native platform for industrial infrastructure planning and techno-economic analysis. | San Francisco, CA |
| Rosebud AI | AI game creation platform — generate games and assets from text prompts. | San Francisco, California, USA |
| Runta | Execution layer and sandboxed runtime infrastructure for production AI agents. | San Francisco, California |
| Rutter | Universal commerce API connecting ecommerce, accounting, and payments platforms. | San Francisco, California |
| Rye | Universal checkout API turning any product URL into a completed order. | San Francisco, CA |
| Safe Superintelligence | AI lab focused on building safe superintelligence — founded by Ilya Sutskever. | Palo Alto, California |
| Samsara | Industrial IoT platform for fleet, equipment, and operations visibility. | San Francisco, California |
| Sandbox VR | Location-based multiplayer VR experiences in proprietary motion-capture arenas. | San Francisco, California |
| Sardine | AI-powered fraud prevention and compliance platform for fintech and crypto. | San Francisco, California |
| Science Exchange | Life-sciences procurement marketplace for outsourced R&D services. | Palo Alto, California |
| SeedFi | Credit-building and savings products for underserved borrowers. | Oakland, California |
| SentiLink | Synthetic identity fraud detection for banks and fintech originations. | San Francisco, California |
| Series Entertainment | GenAI game studio and Rho Engine for AI-native game development. | San Francisco, CA |
| Shef | Marketplace connecting vetted home cooks with local buyers for homemade meal delivery. | San Francisco, CA |
| Sierra | Enterprise AI agents for customer experience—voice and text resolution with outcome-based pricing. | San Francisco, California, USA |
| SignalFx | Cloud-native monitoring platform using streaming analytics. | San Mateo, California |
| Signifyd | Commerce protection platform guaranteeing retailers against fraud and chargebacks. | San Jose, California |
| SigOpt | ML hyperparameter optimization platform for enterprise AI workflows. | San Francisco, California |
| Silver Tail Systems | Real-time web fraud detection using session behavioral analytics. | San Mateo, California |
| Skout | Mobile social network for meeting new people nearby. | San Francisco, California |
| Skydio | Autonomous drones for enterprise inspection, public safety, and defense. | Redwood City, California |
| Slack | Team messaging and collaboration platform for workplaces. | San Francisco, California |
| Smartcar | Unified API connecting apps to vehicle telematics across OEM brands. | Mountain View, CA |
| Snackpass | Social food-ordering app for college campuses and pickup restaurants. | San Francisco, California |
| SnapLogic | Enterprise iPaaS integrating cloud SaaS, databases, and on-premise systems. | San Mateo, CA |
| SocialCam | Mobile social video capture and sharing app. | San Francisco, California |
| Socket | Software supply-chain security for open-source dependencies. | San Francisco, California |
| Solana | High-throughput L1 blockchain for consumer crypto, DeFi, and memecoins. | San Francisco, California |
| Sourcegraph | Code search and AI coding assistant (Cody) for enterprise codebases. | San Francisco, California |
| SpotOn | Restaurant and SMB payments, POS, and marketing software platform. | San Francisco, California |
| Sprig | In-product user research and concept-testing platform for product teams. | San Francisco, California |
| Stainless | Platform generating and maintaining high-quality SDKs from OpenAPI specs. | San Francisco, California |
| Standard Treasury | Banking API platform for developer-first financial institutions (historical). | San Francisco, California |
| Story Protocol | L1 blockchain for registering, licensing, and monetizing intellectual property onchain. | San Francisco, California |
| Stripe | Global payments and financial infrastructure platform for internet businesses. | San Francisco, California / Dublin, Ireland |
| Substack | Publishing platform for independent writers with paid subscriptions. | San Francisco, California |
| Supabase | Open-source Postgres backend platform — database, auth, storage, edge functions, and vector search for developers and AI app builders. | San Francisco, California |
| Superhuman | Premium email client focused on speed and AI-assisted inbox workflows. | San Francisco, California |
| Supersonik | Autonomous multilingual AI agent for live B2B software demos on video calls. | San Francisco, California |
| Swell | Consumer crypto wallet for buying and holding digital assets (historical). | San Francisco, California |
| Swiftype | Hosted site search and enterprise search SaaS. | San Francisco, California |
| Synapse | Banking-as-a-service middleware for fintechs — filed Chapter 11 bankruptcy in April 2024. | San Francisco, CA |
| Syndicate | Infrastructure for creating DAOs, investment clubs, and onchain organizations. | San Francisco, California |
| Tabular | Apache Iceberg table format company for open lakehouse storage. | San Jose, California |
| Talaria | Dynamic web application server with JIT runtime (acquired by Google 2013). | Palo Alto, California, USA |
| Tally | Automated credit-card debt payoff app (shut down August 2024). | San Francisco, California, USA |
| Tecton | Enterprise feature store for real-time ML data (acquired by Databricks 2025). | San Francisco, California, USA |
| Teleport | Identity-based secure access to servers, Kubernetes, databases, and internal apps. | Oakland, California, USA |
| Tessera Labs | AI-native ERP platform automating document-heavy enterprise workflows. | San Jose, California |
| Thatch Health | ICHRA health benefits platform letting employees choose their own insurance. | San Francisco, California, USA |
| The Coterie | Wealth and private-markets platform for founders — alternative investments, estate planning, and lending for asset-rich operators. | Palo Alto, California |
| Tidemark | Cloud FP&A and planning analytics for finance teams (acquired by Vista portfolio company). | Redwood City, California, USA |
| Tigris | Globally distributed S3-compatible object storage built for AI workloads. | Sunnyvale, California, USA |
| Tilt | Social group payments app (acquired by Airbnb 2017). | San Francisco, California, USA |
| TinyCo | Mobile free-to-play game studio (acquired by SGN/GREE 2015). | San Francisco, California, USA |
| Together AI | Neocloud GPU platform for production AI training and open-model inference. | San Francisco, CA |
| Town | Personalized AI assistant that learns your workflows across email, calendar, and docs. | San Francisco, California, USA |
| TripActions | Corporate travel and expense platform — rebranded Navan, IPO October 2025. | Palo Alto, California, USA |
| Truffle Security | Secrets scanning and non-human identity security — makers of TruffleHog. | San Francisco, California, USA |
| Twilio | Cloud communications APIs for SMS, voice, email, and verification. | San Francisco, California, USA |
| TXN Solutions | Consumer spending analytics and competitive intelligence (acquired by Envestnet 2018). | San Francisco, California, USA |
| Udacity | Online tech education platform with Nanodegree programs (acquired by Accenture 2024). | Mountain View, California, USA |
| Ulysses | Modular autonomous surface and underwater vehicles for ocean restoration, infrastructure, and defense. | San Francisco, California |
| Unconventional AI | Brain-inspired, energy-efficient AI chips from former Databricks AI chief Naveen Rao. | San Francisco Bay Area, California |
| Unframe | Managed enterprise AI delivery — implementation and deployment, not model demos. | Cupertino, California |
| UnifyID | Behavioral biometrics for implicit phone authentication; acquired by Prove in 2021. | San Francisco, California |
| Upstash | Serverless Redis, Kafka, and vector database with per-request pricing. | San Francisco, California, USA |
| Urban Engines | Urban mobility analytics from location big data (acquired by Google 2016). | Redwood City, California, USA |
| Valar Labs | Computational pathology AI predicting cancer therapy response from H&E slides. | San Francisco, California |
| Valora | Mobile-first Celo wallet for borderless crypto payments and remittances. | San Francisco, California |
| Vanna Health | Value-based technology-enabled care for serious mental illness (schizophrenia, bipolar). | San Francisco, CA |
| Vanta | Automated SOC 2, ISO 27001, and HIPAA compliance for startups and enterprises. | San Francisco, California, USA |
| Ventrilo | AI application testing that simulates real human UI interaction for QA. | San Francisco, California |
| Very Good Security | Data tokenization and secure custody platform for sensitive information. | San Francisco, California, USA |
| Vesta | Cloud-native mortgage loan origination system (LOS) for banks and lenders. | San Francisco, California |
| VGS | Data security platform tokenizing sensitive data so companies never store raw PII or PAN. | San Francisco, California |
| Wabi AI | Social platform for creating and sharing mini apps via prompts — 'YouTube of apps'. | San Francisco, California |
| Walker & Company Brands | Health and beauty brands for people of color — Bevel grooming (acquired by P&G 2018). | Palo Alto, California, USA |
| Wave | Mobile money and payments platform for Africa (Wave Senegal and beyond). | Dakar, Senegal / San Francisco |
| WaveForms AI | End-to-end native audio language models aiming to pass the speech Turing test. | San Francisco, California |
| Waymark | Community-based care platform extending primary care for Medicaid patients. | San Francisco, California |
| Waymo | Alphabet-backed robotaxi platform operating autonomous ride-hail in US cities. | Mountain View, California |
| Webflow | Visual web development platform for designers and marketing teams. | San Francisco, California, USA |
| Westmag | American-made BLDC motors and actuators for drones and robotics — built in South San Francisco. | South San Francisco, California |
| Wonderschool | Marketplace and OS for in-home preschools and childcare programs. | San Francisco, California |
| WorkBoard | Enterprise OKR and results management platform for strategic alignment. | Redwood City, California |
| World Labs | Spatial intelligence startup building large world models for 3D scene understanding (Fei-Fei Li). | San Francisco, California |
| Worldcoin | Digital identity and cryptocurrency project — proof-of-personhood via World ID. | San Francisco, California, USA |
| xAI | AI company behind Grok — models, X integration, and xAI API. | San Francisco, California, USA |
| Yubico | Hardware security keys (YubiKey) for passwordless and two-factor authentication. | Stockholm, Sweden / Santa Clara, California |
| Zenefits | SMB HR, benefits, and payroll SaaS — acquired by TriNet in 2022, now TriNet HR Plus. | San Francisco, CA |
| Zipline International | Autonomous drone logistics for medical supplies and instant commercial delivery. | South San Francisco, CA |
| Zipline International | Autonomous drone logistics for medical supplies and instant commercial delivery. | South San Francisco, CA |
| Zuma | AI sales engagement converting apartment rental leads via text messaging. | San Francisco, California |
| Zynga | Social and mobile game publisher (FarmVille, Words With Friends) — acquired by Take-Two in 2022. | San Francisco, CA |
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