CA · West
San Francisco Bay Area venture capital & startups
Bay Area frontier AI and enterprise platforms — still the US venture center of gravity.
The Bay Area remains the deepest pool of multi-stage capital for AI, consumer internet, and infrastructure. Pair our SF hubs with national fund profiles.
Funds matched by headquarters aliases; startups by hq field plus curated IDs when verified.
Venture firms in San Francisco Bay Area
Matched from fund headquarters in our directory (alias-based). Dual-HQ firms may appear in more than one city.
| Firm | HQ (directory) | Leads |
|---|---|---|
| 01 Advisors | San Francisco, CA | Series A, Series B+ |
| ARCHIV | San Francisco, California | Series B, Series B+, Series C, Growth |
| Abstract Ventures | San Francisco, California | Seed, Series A |
| Activate Capital | San Francisco, California | — |
| Afore Capital | San Francisco, CA | Pre-Seed, Seed |
| Aldaron | San Francisco and New York, United States | — |
| Alpaca VC | San Francisco, CA | Seed, Series A, Series B+ |
| Alta Partners | San Francisco Bay Area, United States | Series A, Series B |
| Aphias Capital | San Francisco, California | Growth |
| BAG Ventures | San Francisco, United States | Pre-Seed, Seed |
| Base10 Partners | San Francisco, CA | Seed, Series A |
| Benchmark | San Francisco, CA | Series A |
| Bison Ventures | San Francisco, California | — |
| Cantos | San Francisco, CA | Pre-Seed, Seed |
| Craft Ventures | San Francisco, CA | Seed, Series A |
| DCVC | San Francisco, United States | — |
| Define Ventures | San Francisco, CA | Series A |
| Dragoneer Investment Group | San Francisco, California, United States | Growth |
| Fifty Years | San Francisco, California | Pre-Seed, Seed, Series A |
| Firebolt Ventures | Palo Alto and San Francisco, California | Pre-Seed, Seed, Series A |
| First Round | San Francisco, CA | Pre-Seed, Seed |
| Forerunner Ventures | New York, NY & San Francisco, CA | Seed, Series A |
| Foresite Capital | San Francisco, California, United States | Series A, Series B, Series C |
| Framework Ventures | Toronto and San Francisco | Seed, Series A |
| Francisco Partners | San Francisco, United States | Growth, Series C |
| Greenoaks | San Francisco, California | — |
| Haystack | San Francisco, California | Pre-Seed, Seed |
| IndieBio | San Francisco, CA | Pre-Seed, Seed |
| Initialized Capital | San Francisco, CA | Seed, Series A |
| Kindred Ventures | San Francisco, California, United States | Seed, Series A |
| Mischief | San Francisco, California, United States | Seed |
| Neo | San Francisco, CA | Pre-Seed, Seed |
| Reach Capital | San Francisco, California | Seed, Series A |
| SignalFire | San Francisco, California | Seed, Series A, Series B+ |
| Slow Ventures | San Francisco, CA | Seed, Series A |
| South Park Commons | San Francisco, California | Pre-Seed, Seed, Series A |
| Spectrum Equity | Boston, San Francisco and London | Growth |
| Susa Ventures | San Francisco, CA | Seed |
| The Column Group | San Francisco, California, United States | Seed, Series A, Series B, Series C |
| Toyota Ventures | San Francisco Bay Area, United States | — |
| Y Combinator | San Francisco, CA | Pre-Seed, Seed |
Startups we cover in San Francisco Bay Area
Matched from startup hq fields. Many profiles still lack HQ — curated lists
in editorial notes fill gaps when verified.
| Startup | One-liner | HQ |
|---|---|---|
| 11x | AI digital workers for revenue teams — autonomous SDR Alice and voice agent Jordan. | San Francisco, CA |
| AIUC | Certification standard and insurance for enterprise AI agents. | San Francisco, California, USA |
| AKASA | Generative AI platform automating healthcare revenue cycle operations. | South San Francisco, California |
| Abby Care | Clinically supported family-caregiving provider combining caregiver training, pay and care documentation. | San Francisco, California, USA |
| Abridge | AI medical scribe capturing clinician-patient conversations into structured EHR notes. | San Francisco, California |
| Aerodome | Drone-as-first-responder platform for police — automated aerial response to 911 calls. | San Francisco, California |
| AfterQuery | Expert datasets and RL environments that encode how doctors, lawyers, and other practitioners actually work, sold to frontier AI labs. | San Francisco, California, USA |
| AgentMail | API-first email inboxes built for autonomous AI agents. | San Francisco, CA |
| Airbnb | Global marketplace connecting guests with short-term stays and experiences. | San Francisco, California |
| Allswell | Insurance-covered virtual behavioral healthcare focused on the LGBTQ+ community. | San Francisco, United States |
| Amber | RNA-based multi-kilobase gene editing platform for diseases with high allelic diversity. | San Francisco, California |
| Ambience | Ambient AI platform for clinical documentation, medical coding, and health-system workflows. | San Francisco, California |
| Ambience Healthcare | Ambient AI platform for clinical documentation, coding, and health-system workflows. | San Francisco, California |
| Ampersand | Integration infrastructure that lets enterprise AI agents read, write and act inside customer systems of record. | San Francisco, California |
| Amplitude | Product analytics and behavioral data platform for digital teams. | San Francisco, California |
| Anchorage | Regulated crypto custody and banking platform for institutions (Anchorage Digital). | San Francisco, California |
| Angle | Decentralized over-collateralized stablecoin protocol (EURA and USDA). | San Francisco, CA |
| Angle Health | AI-native healthcare benefits platform for small businesses — level-funded plans with broker quoting and care navigation. | San Francisco, CA, USA |
| Anthropic | AI safety company building Claude frontier models, API, and enterprise agents for coding and knowledge work. | San Francisco, California |
| AnyRoad | Experience relationship management platform for brand activations and events. | San Francisco, CA |
| Anyscale | Commercial platform for Ray distributed computing — scale AI/ML workloads on any cloud. | San Francisco, California |
| Apollo | GraphQL platform (Apollo GraphOS) for unified API development at enterprise scale. | San Francisco, California |
| Aradigm | Benefits platform enabling sustainable employer access to cell and gene therapies. | San Francisco, California |
| Arcee AI | U.S. open-weight foundation models (Trinity) plus tools to customize and deploy them. | San Francisco, California, USA |
| Arda Therapeutics | Targeted cell-depletion therapies for chronic diseases using oncology modalities outside cancer. | South San Francisco, California |
| Arena | AI evaluation platform behind Chatbot Arena / LMArena leaderboards. | San Francisco, California |
| Armada | Modular edge AI data centers and full-stack edge computing platform. | San Francisco, CA |
| Asana | Work management and team collaboration software. | San Francisco, California |
| Asserts | Contextual observability intelligence for Prometheus and OpenTelemetry metrics. | San Francisco, CA |
| Asserts.ai | Observability contextual intelligence for Prometheus/OpenTelemetry (acquired by Grafana). | San Francisco, CA |
| Astranis | Small geostationary satellites delivering dedicated regional broadband connectivity. | San Francisco, California |
| Astro Mechanica | Supersonic turboelectric adaptive jet engine and aircraft developer. | San Francisco, California |
| Atlys | Digital visa application platform for international travelers. | San Francisco, California |
| AusperBio | Clinical-stage oligonucleotide company developing ASO and targeted-siRNA candidates aimed at a functional cure for chronic hepatitis B. | San Francisco, CA (U.S. entity); China operations for the AHB-137 Phase 3 program |
| Authy | Two-factor authentication API for developers and enterprises. | San Francisco, CA |
| Automatic | OBD-II connected car adapters and apps for diagnostics, safety, and usage-based insurance. | San Francisco, California |
| BBA Inc | Meldium — team SSO and cloud app password management, acquired by LogMeIn in 2014. | San Francisco, California |
| BackOps | AI resolution layer for companies that make or move physical goods — claims, disputes, billing. | San Francisco, California, USA |
| Baseten | AI inference platform for deploying, serving, and autoscaling production models with OpenAI-compatible APIs. | San Francisco, California |
| Beacons | Creator business platform for link-in-bio sites, storefronts, and audience monetization. | San Francisco, CA |
| Bedrock Robotics | Retrofit autonomy kit turning 20–80 ton excavators into supervised self-driving earthmovers on construction sites. | San Francisco, California |
| Belong | Residential rental marketplace replacing landlord–tenant friction with homeowner–resident relationships. | San Francisco, California |
| Benchling | R&D cloud platform — the operating system for life science labs. | San Francisco, California |
| BigScreen | Social VR platform and Bigscreen Beyond micro-OLED headset hardware. | San Francisco, CA |
| Black Ore Technologies | AI platform automating tax prep and financial-services workflows (Tax Autopilot). | San Francisco, California |
| Blacksmith | Managed computing infrastructure for building and testing software, including code produced by AI agents. | New York / San Francisco |
| Blend Labs | Digital lending platform for mortgages and consumer banking (NYSE: BLND). | San Francisco, California |
| Bounce | Global luggage storage marketplace for travelers. | San Francisco, California |
| Braid.ai | Creator-economy analytics and direct-to-fan tools (Braid.ai). | San Francisco, California |
| Braintrust | AI evaluation, observability, and prompt tooling for production LLM products. | San Francisco, California |
Related reading
San Francisco Bay Area FAQs
Practical answers for founders researching this investor.
Open /vc/san-francisco-bay-area for fund HQ matches from our directory, then related reading for editorial shortlists.
See the startups table on /vc/san-francisco-bay-area. Profiles link to /startup/ pages when HQ or curation matches.
Start at /vc/san-francisco-bay-area, then the related blog hub and /directory for national funds.