Venture and advisory firm founded by former Twitter executives Dick Costolo and Adam Bain to help post-PMF technology companies scale go-to-market and operations.

Thesis-driven pre-seed and seed firm based in New York and Boston, leading $500K–$3M checks in Vertical AI, deep tech, healthcare, and biotech.

Buffalo accelerator investing $5M/year; five companies get $1M each plus a year-long program at Seneca One; equity is 5% via warrant. Companies must relocate the CEO and at least 50% of staff to Buffalo. Notable graduate: ACV Auctions (IPO).

Corporate venture arm of Blue Cross and Blue Shield of Alabama, making strategic equity investments in healthcare and health-tech companies relevant to the payer and care ecosystem.

NYC/SF data-driven early-stage firm (founded 2014) leading seed and Series A in software, infrastructure, and consumer tech — known for its Voyager sourcing platform and Fund IV / Select Fund I follow-on model.

Joe Lonsdale's Austin-based firm backing and building technology companies across defense, advanced manufacturing, healthcare, logistics, and enterprise software.

Colorado venture firm founded in 1999 investing $250K–$2.5M in seed and Series A technology companies across SaaS, cybersecurity, AI, and marketplace models. Main office in Westminster, CO with a Denver office at Industry Denver (3001 Brighton Blvd); 100+ portfolio companies and $125M+ raised across fund vehicles per firm materials.

San Antonio pre-seed venture firm founded in 2017 by entrepreneur Pat Matthews (ex-Webmail.us / Rackspace). Backs technical founders building AI-native enterprise software and cloud infrastructure. Typical checks $100K–$1M with ability to follow; closed Fund III at $28M+ (2025). HQ at 110 E Houston St, San Antonio, TX; also invests nationally from a Texas base.

London pre-seed and seed firm backing overlooked founders in climate equity, economic empowerment, and healthy ageing across the UK and Northern Europe.

New York multi-stage firm founded by Lee Fixel (ex-Tiger Global), managing ~$6.3B+ and writing concentrated seed-to-growth checks into founder-led category leaders across enterprise, fintech, and AI infrastructure.

San Francisco pre-seed specialist co-founded by Anamitra Banerji and Gaurav Jain, leading first institutional rounds for product-oriented software founders.

Andrew Ng's Palo Alto venture studio co-founding AI companies alongside recruited CEOs, backed by $370M+ in committed capital.

Alabama-focused $25M seed fund managed with Redhawk Advisory; Fund I closed in 2018. Fund I is not currently accepting new submissions—founders should treat the vehicle as closed for new applications unless the firm announces otherwise.

San Antonio angel network (founded 2016 as San Antonio Angel Network; rebranded Alamo Angels in 2017) providing seed and early-stage capital, education, and deal flow for Texas entrepreneurs. Associated with VelocityTX / Texas Research & Technology Foundation ecosystem. Members are accredited investors syndicating into technology and life-science startups.

Charleston, South Carolina evergreen venture firm focused on early-stage B2B software and technology-enabled services across the Southeast — typically after initial traction, partnering with other institutional investors.

Kevin Ryan's New York venture studio and early-stage fund that both incubates companies and leads pre-seed through Series A investments across healthcare, enterprise tech, and economic infrastructure.

NYC office / Corigin Ventures heritage entry for Alpaca VC — commerce infrastructure, PropTech, and real-world economy from early seed through Series A. Canonical product firm profile is also /fund/alpaca-vc (SF HQ); same website alpaca.vc.

Primary Alpaca VC profile (San Francisco HQ): early-stage firm backing founders deploying intelligence across foundational industries — manufacturing, logistics, energy, construction, defense, and commerce infrastructure. Same brand/site as the NYC office/heritage entry at /fund/alpaca-vc-nyc (alpaca.vc).

Research-driven New York venture firm using data science and behavioral science to back seed and Series A companies unlocking new markets.

Brad Gerstner's crossover technology investor managing public equity and private growth funds from Menlo Park, backing category-defining software and internet companies.

New York–based early-stage firm founded by Tricia Black (Facebook’s first VP of Sales) that backs companies with women in executive leadership across commerce, care, and connectivity. The firm reports it is no longer making new investments but continues supporting its portfolio.

Andreessen Horowitz (a16z) is a Menlo Park multi-stage firm with $35B+ AUM, running thematic practices across AI, crypto, enterprise, bio, and American Dynamism — from seed through growth, with platform-scale founder support.

Seed-stage firm investing $500K–$2.5M in U.S. companies from ideation through early traction, with a focus on developer tools, productivity software, and marketplace businesses. Known portfolio includes WorkOS and The Browser Company.

Global day-zero investor and company builder operating in 26+ locations, backing founders from inception through pre-seed and seed with capital, community, and residency-style programs.

Ann Arbor healthcare VC founded 2002. Manages ~$1B across six funds; Fund VI closed at $268M (June 2023). Focus: medical devices, life science tools & diagnostics, tech-enabled care, pharma adjacencies — with preference for under-ventured geographies including the Midwest. Main office: First National Building, 201 S. Main Street, Suite 300, Ann Arbor, MI 48104.

Chicago-based life-sciences specialist that co-founds and funds seed through growth-stage biotech and deep-science companies, often originating companies directly from academic research.

Phoenix and Scottsdale seed fund (AzFF) established in 2016 as Arizona's first dedicated software seed vehicle — writing $50K–$400K checks with a network of operator-founders providing hands-on support.

Seattle pre-seed venture firm founded in 2019 by Kirby Winfield, focused on Pacific Northwest founders building vertical AI agents, Gen AI infrastructure, and AI applied to physical industries. Fund I deployed from a $15M vehicle (2019); Fund II closed at $25M in May 2023. Typical first checks run $250K–$750K with $500K as a common sweet spot. Ascend positions itself as the most active pre-seed investor in the region.

Founded by former Tiger Global partner Sam Giber. Focuses on early-stage technology investments with a global perspective.

Atlanta venture firm and startup studio founded in 2012 by David Cummings (Pardot/Salesforce exit). Atlanta Ventures leads $250K–$5M seed through Series B rounds in Southeast SaaS and subscription businesses, runs a co-founding Studio, and anchors the Atlanta Tech Village ecosystem.

Cambridge, MA–based biotech venture firm that creates and builds early-stage life-sciences companies, partnering with scientists from company formation through Series A.

Austin early-stage venture firm founded in 2014 (formerly ATX Seed Ventures), investing in applied AI across defense and space, industrial operations, healthcare, and financial infrastructure. Operator-founded team based downtown at 500 W 2nd Street.

Global venture firm co-founded by Eduardo Saverin, investing across early through late stage in technology, healthcare, and energy/resilience. Reports $12B+ AUM and 200+ portfolio companies with a strong New York presence at Hudson Yards.

The venture arm of Bain Capital. Portfolio includes GoTo, Redis, and Clari, focusing on enterprise software and growth-stage investments.

London-based venture firm investing in European technology companies from seed through growth, with $615M Early Stage Fund IX and $685M Growth Fund II raised in 2024.

San Francisco firm investing in automation for the real economy — fintech, logistics, commerce, and operations-heavy sectors — from seed through Series B. Reports $2.6B AUM after a 2025 $850M raise; donates 50% of profits via the Advancement Initiative.

Boston-founded global technology investor (since 1983) backing application software, infrastructure, consumer, and industrial tech. Investing from Battery Ventures XV, a $3.25B flagship fund.

Early-stage firm known for its equal-partnership model and concentrated Series A investments.

One of the oldest venture firms in the U.S., with offices in New York, Silicon Valley, Israel, and India. BVP backs early-stage and growth companies across enterprise SaaS, cloud infrastructure, fintech, and healthtech — known for the BVP Cloud Index and long-horizon category bets.

New York–based venture firm and startup studio behind early bets on Giphy, Anchor, and TweetDeck. Betaworks runs Camp accelerator programs and, as of 2025, closed a $66M Fund III focused on pre-seed and seed AI startups.

St. Louis company-creation and early-stage investor focused on healthcare and agriculture. Part of the BioSTL ecosystem; BioGenerator dates to 2003 as a regional life-science formation engine. BioGenerator Ventures builds companies from concepts/EIRs, invests from an evergreen model, and syndicates with national venture and strategic capital. Sectors: therapeutics, diagnostics, research tools, and agtech. HQ St. Louis, MO.

Atlanta multi-stage venture platform (division of BIP Capital) founded in 2007 connecting founders with growth capital across fintech, enterprise SaaS, healthtech, insurtech, and infrastructure software. HQ at Piedmont Center, 3575 Piedmont Rd NE — formerly operated as Panoramic Ventures (2021–2023).

Pittsburgh- and San Francisco–based early-stage venture firm founded in 1996. Invests seed and Series A in SaaS, marketplace, and mobile/tech companies nationally, with deep Pittsburgh roots. HQ address listed as 2000 Smallman Street, Suite 201, Pittsburgh, PA 15222; also lists a San Francisco office. Firm site cites over $250M under management.

B Corp–certified transatlantic growth investor with offices in Paris and New York. Known for mission-driven consumer bets including Spotify, Pinterest, and Headspace; launched a dedicated climate technology fund in 2024.

New York–based early-stage venture firm investing exclusively in blockchain protocols and crypto infrastructure. Founded in 2018, Blockchange backs founders building decentralized networks, wallets, and on-chain data systems.

Honolulu accelerator and early-stage investor helping founders build companies with Asia-Pacific relevance from Hawaiʻi. Cohort-based program with demo-day visibility across the Pacific.

NYC-based 'day one' investor for technical founders building developer tools and enterprise SaaS. Backed Snyk and BigID; closed Fund VII at $250M in July 2025 with $500K–$15M inception-stage checks.

New York early-stage firm founded in 2009, known for being among the first checks in companies like Ramp, Plaid, and Airtable. BoxGroup writes pre-seed and seed rounds across sectors with a generalist, founder-first approach.

Minneapolis early-stage firm investing in food, ag, and related technology companies — thesis-aligned with Midwest industry strengths.

Chattanooga pre-seed/seed firm and founder outpost. Writes roughly $100K–$500K checks and requires portfolio founders to relocate to The Yard in Chattanooga until ~$1M ARR or shutdown — an insulator model, not a cohort accelerator.

Milwaukee 501(c)(3) venture philanthropy foundation investing donated capital into Wisconsin early-stage tech companies; returns recycle into new investments. Address: 710 N. Plankinton Ave., Ste. 340, Milwaukee, WI 53203.

Des Moines broker-led insurtech ecosystem and accelerator founded in 2019 at 500 Locust Street. Runs the BTV Accelerator ($50k per cohort company) and, with ManchesterStory as GP, launched the $34M BrokerTech Fund LP in May 2023 — the first venture fund backed by a consortium of leading insurance brokers for broker-centric insurtech.

Birmingham nonprofit early-stage CDFI and investment accelerator. Through VentureLab and its Investment Accelerator (gener8tor partnership), public terms are often cited as $100k for 5% on a SAFE over a 12-week program.

The first venture fund based in Brooklyn, founded by Charlie O'Donnell in 2012. Backs pre-seed and seed companies in consumer, marketplace, and B2B software — portfolio includes The Wing and Canary.

$10M evergreen early-stage fund affiliated with University at Buffalo Startup Ventures; capitalized via New York State ESD Innovation Hub and the SUNY Research Foundation. Cultivator investments up to $100k; Seed investments up to $250k with a 1:1 match requirement to non-NYS funds.

PropTech-focused venture firm founded in 2011, investing across real estate technology from construction to property management. Portfolio includes VTS and Notarize; backs vertical SaaS and data platforms serving landlords, brokers, and tenants.

Multi-stage venture firm founded in 1987 with offices in New York and the Bay Area. Canaan backs fintech and healthcare companies from seed through growth — public portfolio includes LendingClub and The RealReal.

San Francisco–based early-stage firm founded in 2021, investing at the intersection of software, hardware, and wetware. Cantos closed Fund IV at $70M in 2026, backing defense, climate, and deep-tech founders at pre-seed and seed.

Boise / Meridian, Idaho venture firm investing in early-stage technology companies across the Mountain West and nationally. Active participant in Idaho ecosystem deals (e.g. GetWhys seed).

Boise, Idaho seed venture firm founded by Matthew Colford, backing pre-seed and seed technology companies (enterprise software, SaaS, AI). SEC Form D for Carpenter Capital Fund I LP lists principal place of business at 425 Pueblo St, Boise, ID 83702. Website: carpentercapital.vc.

Jacksonville manufacturing-tech venture fund (founded 2024) investing in disruptive robotics, automation, and industrial technology addressing labor shortages, energy transformation, healthcare manufacturing, and environmental remediation.

New York pre-seed and seed firm founded in 2015, backing technical founders at company inception. Portfolio includes Transfix and Cometeer; known for being among the earliest institutional checks in NYC startups.

Charleston, South Carolina angel group investing in early-stage Southeast companies.

Charlotte-based angel fund investing in early-stage Southeast companies, with emphasis on the Charlotte banking/fintech corridor.

Charlotte-based venture fund investing in the city’s highest-quality technology companies at pre-seed/seed in the Charlotte metro and later-stage companies across the Carolinas. Launched in 2022 with LaunchCLT; partners Mark McDowell and Don Rainey closed Charlotte Fund II in 2024. HQ: Charlotte, NC (SEC Form D lists 2101 Beverly Drive).

Chattanooga angel capital fund investing in seed and early-stage Southeast companies — including lasting local HQs such as Branch Technology and Variable. CRF I/II portfolio spans software, advanced manufacturing, and consumer brands rooted in Gig City.

Chicago seed-stage venture firm (Merchandise Mart) that leads early rounds for technology companies and partners hands-on through the first institutional years. Thesis spans supply chain and logistics, fintech, healthcare, enterprise tools, proptech, mobility, and related software — with a bias that enduring companies can be built outside coastal hubs. HQ: 222 W. Merchandise Mart Plaza, Chicago, IL.

Louisville-based venture firm investing in healthcare and technology companies across the Midwest and South. Long-running Kentucky institutional VC presence.

Cincinnati seed-stage firm and one of the Midwest’s most active seed investors, supported by Ohio Third Frontier and founding partners including Cincinnati Children’s, University of Cincinnati, and the Cincinnati USA Regional Chamber. Address: 2900 Reading Rd. Ste. 410, Cincinnati, OH 45206.

Midwest healthcare VC formerly Venture Investors Health Fund (founded 1984). ~$350M AUM. Madison HQ at University Research Park (510 Charmany Drive, Suite 250, Madison, WI 53719) with Ann Arbor and Milwaukee offices. Early-stage medtech and life sciences.

Chattanooga startup accelerator and commercialization program (thecompanylab.org / company-lab) helping early teams validate ideas and connect to capital in the Gig City ecosystem.

New York technology investment firm founded in 1999, spanning public equities and private markets from venture through growth. Coatue is known for crossover rounds in consumer internet, enterprise software, and AI — backing companies like Snap, DoorDash, and OpenAI.

New York venture firm founded in 2010, backing companies 'pushing the world forward' across climate, consumer health, and sustainable food. Early investor in Lyft, Sweetgreen, Impossible Foods, and WHOOP; launched Collab SOS, a $200M climate fund.

New York early-stage firm tied to the Grand Central Tech campus. Runs a zero-equity, zero-rent founder residency and writes pre-seed and seed checks—typically around $250K–$1.5M—for teams building venture-scale software, often in AI, healthcare, fintech, and enterprise SaaS.

New York thesis-driven deep-tech firm led by Michael Dempsey. Known for research-heavy, n-of-1 investing across AI/ML, robotics, biology, crypto, and frontier infrastructure—often backing technically ambitious teams before categories are obvious.

New York seed-stage firm founded in 2005, focused on enterprise SaaS and fintech. Contour typically leads pre-seed and seed rounds for B2B software companies with early commercial signal.

Scottsdale early-stage venture firm (formerly AZ-VC) investing Series A in non-coastal North American software companies — Fund I deployed $115M+; Fund II launched September 2025 targeting $300M with a disciplined valuation thesis.

Oklahoma City early-stage venture firm investing in technology companies between the coasts. Notable OKC portfolio includes Apricot Health (AI home-health documentation).

Southwest deep-tech venture firm (founded 2010) investing in patent-based hard science at pre-seed and seed — photonics, advanced materials, nanotechnology, robotics, medical technology, and climate hardware. Offices in Santa Fe, Denver, and the Netherlands; Fund IV first close March 2025 targeting $80M.

Orange County early-stage venture fund investing in Southern California technology companies from the OC / Irvine ecosystem.

Palo Alto and New York seed fund founded in 2012 by Aileen Lee, who coined the term 'unicorn.' Purpose-built for pre-seed and seed—Cowboy says roughly 70% of its investments are pre-product—and known for hands-on support through seed-to-Series A.

San Francisco firm co-founded by David Sacks and Bill Lee in 2017. Operator-led investor backing B2B SaaS and marketplace companies from seed through growth, with playbooks drawn from building and scaling unicorn businesses.

European early-stage firm founded in 2003, with offices in Stockholm, Berlin, London, and San Francisco. Early backer of Spotify and Klarna; leads seed and Series A rounds for ambitious founders building global technology companies from Europe.

Charlotte-based growth equity firm investing in AI-forward B2B companies from early growth/seed through later private stages before IPO. Operates a capital-plus-capabilities studio model; HQ at 201 South College Street, Suite 2700, Charlotte, NC. Backed Charlotte-area companies such as DebtBook.

Santa Monica seed-stage venture firm founded in 2008 — among LA's longest-standing seed funds. Invests $1M–$3.5M in frontier tech: energy transition, space economy, defense systems, advanced manufacturing, and robotics. Public materials cite $300M+ committed across five funds.

Cambridge, MA early-stage firm founded in 1970 (formerly Charles River Ventures). Refocused on seed and Series A with its $750M CRV XX fund; backed DoorDash at seed and led Series A rounds in companies like Mercury and Vercel.

St. Louis early-stage venture firm founded in 2012. Manages a family of funds focused on seed and Series A across life sciences/health tech, software & IT, agriculture tech, and geospatial tech. Initial checks publicly described in the $100k–$3.5M range; the firm says it leads about half the rounds it joins. HQ at 911 Washington Ave, Suite 801, St. Louis, MO.

New York crossover investment firm founded in 2018 by Dan Sundheim. Deploys large checks in late-stage private technology and consumer companies alongside a concentrated public-equities book—not a traditional seed or early-stage VC.

Irving/Dallas-area early-stage venture firm (DVC) founded in 2021, investing in B2B SaaS across cloud infrastructure, cybersecurity, DevOps/AIOps, data, and related enterprise AI themes. U.S. office: 222 W. Las Colinas Blvd, Suite #755E, Irving, TX 75039; also operates India fund activities from Hyderabad. Firm site cites cumulative capital deployed and an active DVC Advantage platform for portfolio support.

Orlando early-stage VC (founded 2015; formerly FAN Fund) investing Seed and Series A in technology and life sciences, primarily in Florida and other undercapitalized U.S. regions. Office: 1000 Legion Place, Suite 830, Orlando, FL 32801.

Charlotte-based venture builder that invests capital and operational support into B2B enterprise technology companies. Founded in 2020 by John Espey and Tareq Amin; HQ at 1920 Cleveland Avenue, Suite B, Charlotte, NC. Combines direct funding with shared services (product, cloud, go-to-market) rather than a classic seed-only fund model.

San Francisco digital-health venture firm founded in 2020 by Lynne Chou O'Keefe (formerly Kleiner Perkins). One of the larger early-stage funds focused exclusively on health tech—from incubation and seed through Series B.

Denver early-stage venture platform (denverventures.co) that grew out of the Denver Angels investor community. In 2025 the firm announced Denver Ventures Seed Fund I (oversubscribed ~$20M) and stated it manages over $60M across vehicles, deploying into pre-seed/seed technology companies and later-stage opportunities via affiliated growth vehicles. HQ and team are Denver-based.

Tucson-based nonprofit angel network of accredited investors. Founded 2000; members report $62.5M+ invested into 165+ companies and sidecar SPVs. Accepts preferred equity or convertible notes (not SAFEs) for North American early-stage companies; monthly screening via Dealum.

Detroit early-stage venture firm founded in 2010 by Dan Gilbert (Rocket Companies) to back tech founders and grow Detroit’s entrepreneurial community. Invests seed and Series A; portfolio companies can access the Rock Family of Companies network. HQ Detroit, MI. Website: detroit.vc.

New York holding company and investor in the crypto industry, founded by Barry Silbert in 2015. Operates and backs businesses including Grayscale and CoinDesk, with 200+ equity investments across blockchain infrastructure, DeFi, and digital assets.

Columbus, Ohio venture firm founded by former Sequoia investors Mark Kvamme and Chris Olsen (firm dates itself to 2012–2013). Invests in market-defining companies across the U.S./Canada with Midwest roots. HQ commonly listed at 629 N. High Street, Columbus, OH 43215. Public Form ADV-era materials have reported multi-billion regulatory AUM.

Omaha-based early-stage firm investing in commerce enablement and supply-chain technologies from website to warehouse. Public materials cite ~$90M AUM, 50+ founders, and leading 80%+ of deals at pre-seed/seed. HQ: 3717 Harney St, 2nd Floor, Omaha, NE.

Tucson venture arm of Diamond Ventures (founded 2018) investing micro-cap Series A and early institutional rounds in Southwest technology. Focus areas include enterprise software, AI, cybersecurity, 5G infrastructure, and national-security-adjacent B2B — with emphasis on women- and minority-led founders per launch materials. Portfolio ties include UA spinouts such as Freefall Aerospace / ED2 lineage.

Lawrenceville, New Jersey growth-equity and venture firm (formerly Edison Ventures) investing in fintech, healthcare IT, and vertical SaaS companies outside Silicon Valley — typically $5M–$10M initial checks into businesses with roughly $10M–$30M revenue.

Early-stage investor listed in our directory as New York–based (founded 2019), focused on companies led by female and diverse founders. Public fund materials are limited—no website is listed in our records—and coverage should be treated as incomplete pending verification.

Honolulu-based 501(c)(3) nonprofit investor deploying catalytic capital and project expertise to climate technologies with deep local impact. Formerly Elemental Excelerator; portfolio of 160+ companies in energy, agriculture, transportation, industry, and nature-based solutions.

Portland venture firm investing in diverse founders and early-stage technology companies in the Pacific Northwest.

Indiana early-stage venture firm that deploys state-linked and private capital into Indiana startups. A common first institutional check for Indy and statewide founders across software, health, and advanced industries. HQ Indianapolis, IN. Founders typically pitch Elevate alongside local studios and angels before coastal Series A.

New York climate and energy-transition investor founded in 2015. Brings together entrepreneurs and corporate strategic partners (utilities, industrials) to back companies decarbonizing power, grid, mobility, and industrial systems.

Houston early-stage VC founded in 2020 by Craig Lawrence and Neal Dikeman — positioned as Texas’s first fund exclusively dedicated to energy-transition technologies. Invests Seed–Series B (selective later) across distributed energy, electrification, mobility, resource efficiency, and enabling software. First fund targeted ~$75M with GS Futures/GS Energy as early anchors (2021 launch).

New York seed fund founded in 2009, one of the earliest dedicated seed firms. Leads pre-seed and seed rounds with checks typically from $350K to $3M (Eniac V, $125M); known for backing Anchor and Hinge and a high seed-to-Series A graduation rate.

Santa Barbara late-seed venture fund (founded 2018) that works hands-on with a small cohort of enterprise and industrial tech companies from product-market fit through first institutional Series A. Operator-led team with Silicon Valley and Central Coast presence.

New York seed firm founded in 2019 by Richard Kerby and Rick Zullo, investing in climate, insurance, retail, and supply-chain startups that modernize legacy industries. Raised $175M for Fund II and a debut Opportunity Fund in February 2025.

Rochester / Upstate New York seed fund investing up to ~$1.5M in early-stage high-tech companies. Founded with University of Rochester and Empire State Development ties; sectors include medical devices, materials, energy, biotech, agtech, imaging, and IT/software.

Startup studio and early-stage venture firm founded by Uber co-founder Garrett Camp in 2013, combining company-building support with pre-seed and seed investments in New York and San Francisco.

Cambridge-based venture firm affiliated with Fidelity Investments, with a heritage tracing to Fidelity's venture arm. Self-capitalized investor in life sciences, healthtech, enterprise software, fintech, and frontier technology across North America and Europe.

Los Angeles-based venture firm focused on proptech and the built world, backed by a strategic LP base of real-estate owners and operators. Invests from seed through growth in technology reshaping property, construction, and climate-adjacent infrastructure.

Birmingham early-stage firm with a Life Science Fund I focused on UAB/Birmingham life sciences and an Opportunity Fund for seed and pre-seed companies; Opportunity Fund commitments exceeded $2M as of April 2024, with typical Opportunity Fund checks of $100k–$500k.

San Francisco-headquartered seed pioneer founded in 2004, backing founders from pre-seed through Series A with a community platform and 560+ portfolio companies including early bets on Uber, Roblox, Notion, and Square.

New York office of First Round Capital—the seed pioneer behind Uber, Roblox, and Square. Same firm as /fund/first-round, with a community-first platform supporting pre-seed and seed founders in NYC and nationally.

New York early-stage venture firm founded in 2008 with $2B+ AUM, backing enterprise software, fintech, and consumer internet. Known for community programs including Data Driven NYC and portfolio support beyond capital.

Colorado seed firm (firstmilevc.com) founded in 2014, headquartered in Colorado Springs with Denver and Austin presence. Aims to be an early partner to founders building companies in major tech hubs outside the coasts — especially Colorado and Texas. BusinessDen reported a ~$25M third fund in 2026 with typical checks cited in the mid-six-figure range and a majority of investments expected in Colorado.

New York venture firm co-founded by Fabrice Grinda, among the world's most active marketplace investors. Writes programmatic pre-seed through Series A checks and typically co-invests rather than leading rounds.

Palo Alto micro-VC founded in 2008 by Mike Maples Jr. and Ann Miura-Ko, known for pioneering small early-stage funds and early bets on Lyft, Okta, and Twitch.

Tampa-based venture firm and accredited investor network investing in early-stage B2B tech from pre-seed through Series B. Public materials cite $300M+ deployed across 100+ portfolio companies; office listed at 1311 N. Westshore Blvd. #101, Tampa, FL.

Jacksonville-headquartered venture capital fund (founded 2022) investing in high-tech startups and later-stage companies with a Florida-first thesis and selective opportunities beyond the state. Provides capital plus network access for founders building in Florida's innovation economy.

Seattle early-stage venture firm founded in 2016, investing exclusively in artificial intelligence and machine learning startups. Fund I closed at $37M (2018); Fund II at $70M (May 2022). The team targets pre-seed and seed rounds — roughly $1M pre-seed and $2M seed on average — with about 70% of capital dedicated to Pacific Northwest companies and selective U.S., Canada, and UK deals.

Kansas City early-stage venture firm founded in 2014. Thesis is backing underestimated technology founders transforming the ‘Flyover’ region — investing early with conviction and staying hands-on through the hard parts. Portfolio highlights on the firm site have included companies such as EyeVerify/Zoloz, Opendorse, and Verusen. HQ Kansas City, MO.

Davis, CA angel network born from the UC Davis and Greater Sacramento food-and-health ecosystem. Invests in early-stage companies applying science, data, and technology to metabolic health, performance, and healthy longevity. Members pool capital via per-deal SPVs; site cites seed checks in the $100K–$3M range.

Consumer-focused venture firm founded by Kirsten Green in 2012, backing digital-native brands and commerce infrastructure. Portfolio includes Glossier, Hims & Hers, and Away, with growing bets in AI-native infrastructure.

New York pre-seed fund and B2B SaaS accelerator founded in 2014, investing $100K per company through a 16-week program. Focuses on enterprise software and AI tools from first check through seed readiness.

San Francisco and New York venture firm founded in 2005, backing ambitious founders in deep tech, AI, defense, and space. Known for early bets on Facebook, SpaceX, Palantir, Stripe, and Anduril with $3B+ AUM.

Seattle seed-stage venture firm founded in 2008, positioning itself as the Pacific Northwest's leading first-check investor for ambitious technical founding teams. Fund VI closed at $50M in November 2025 (matching Fund V), targeting roughly 30 companies with average initial checks of $1M–$1.5M and ~10% ownership at first investment. Portfolio includes Remitly, Outreach, and Auth0 (Okta acquisition).

Boulder, Colorado network-driven venture firm (foundry.vc; historically Foundry Group) founded in 2007 by Brad Feld, Seth Levine, Ryan McIntyre, and Jason Mendelson. Invests in early-stage technology companies and early-stage venture funds. HQ commonly listed in Boulder (e.g. Walnut Street). Public materials describe Foundry 2022 as a $500M fund and the firm’s final fund while partners continue deploying and supporting the portfolio.

Nashville healthcare venture firm co-founded in 2016 by former U.S. Senate Majority Leader Bill Frist, MD and Bryan Cressey. Backs early-stage companies transforming care delivery with technology and tech-enabled services, including AI-native models. Closed oversubscribed Fund IV at $425M (Feb 2026 PR), bringing firm AUM toward ~$1B. Strategic LP network includes The Cigna Group, MedStar Health, and OhioHealth. HQ at 40 Burton Hills Blvd, Nashville, TN.

Charlotte growth-equity firm (formerly Frontier Capital) backing lower-middle-market vertical SaaS and tech-enabled services. Typical initial equity $5M–$30M for companies with roughly $3M–$20M ARR — a later-stage complement to Charlotte Angel Fund and RevTech seed capital.

Defunct venture arm of the collapsed cryptocurrency exchange FTX, active from 2021 until FTX's November 2022 bankruptcy. Portfolio stakes were subject to estate proceedings; the firm is not making new investments.

Miami-headquartered venture firm founded in 2017 (originally Wynwood; HQ later moved to Coconut Grove / “Fuel Station” at 2901 Florida Avenue). Backs technology companies across seed through growth with a public-markets-informed “phased investment” approach. Public portfolio and marketing materials emphasize fintech, marketplaces, enterprise software, consumer tech, and related categories; known names associated with the firm include Replit, CookUnity, and RecargaPay.

Reno-based pre-seed venture fund affiliated with StartUpNV, Nevada's statewide accelerator. Invests in revenue-generating Nevada startups (or companies relocating to Nevada) that complete the StartUpNV accelerator pipeline. Reno office: 450 Sinclair Street. Typical initial checks around $50k–$100k via SAFE or convertible note, with Nevada SSBCI 1:1 match available on qualifying investments.

Lu Zhang's Palo Alto firm backing early-stage deep-tech, healthcare, and enterprise AI companies with technical or data moats. Deploying from Fund IV ($190M, closed March 2025).

One of the largest investment syndicates backing LGBTQ+ founders and allies, deploying across pre-seed through Series A with a global member network.

Global venture firm and accelerator network headquartered in Madison, Wisconsin (821 E Washington Avenue, Suite 200-G, Madison, WI 53703), with Milwaukee and Minneapolis offices. Runs cohort accelerators across 40+ communities; FAQ states HQ is Madison.

New York presence of General Catalyst, the multi-stage firm founded in 2000. Same partnership invests from seed through growth across AI, health, fintech, and enterprise globally.

Multi-stage venture firm founded in 2000, investing from seed through growth across AI, health, fintech, and enterprise software. Headquarters in Cambridge, MA with global offices including New York.

Global venture firm with a significant New York office, backing enterprise SaaS and consumer companies from seed through growth. U.S. and Asia operations were reorganized into separate entities in 2024–2025.

Early-stage venture firm investing in transformative science and technology. Majority women-owned; offices in Charleston, SC (11 eWall Street / Mount Pleasant) and Boston.

Minnesota early-stage venture firm investing in technology companies across the Upper Midwest.

Venture firm with offices in New York and Los Angeles, investing from pre-seed through growth in consumer, enterprise SaaS, and fintech. Raised new funds totaling roughly $1B in 2025.

One of the longest-standing U.S. venture firms (founded 1965), backing enterprise and consumer founders from seed through growth. Notable investments include LinkedIn, Airbnb, Figma, and Wiz.

Greater Sacramento early-stage venture firm and studio founded in 2021 by Mark Haney, Rick Spencer, and partners. Public materials cite 70+ portfolio companies, $22M+ AUM (indicative), and exits including OnSight Technology (2024). Invests in B2B SaaS, AI, climate, and regional founders from the Sacramento / Roseville corridor.

Orlando Lake Nona health innovation center (opened 2016) under GuideWell Mutual Holding Corporation. Hosts startups/scaleups, events, and a Plug and Play–partnered HealthTech Accelerator at 6555 Sanger Road, Orlando, FL 32827 — commercialization hub more than a classic LP venture fund.

Mission-driven New York firm founded in 2015, investing $1–2.5M at pre-seed and seed in diverse founders across four AI-driven themes. Deploying Fund III with 70+ investments to date.

Research Triangle life-science venture firm investing in biotech, medical devices, and healthcare companies from Durham / Raleigh–Durham.

Hawaiʻi-based angel network of accredited investors funding early-stage companies connected to the islands' economy and Pacific opportunity set.

SoftBank-backed hardware / hard-tech accelerator historically operating a U.S. program presence in Newark, New Jersey. Helps deep-tech and hardware founders from prototype through early institutional rounds. Program details at hax.co.

Global venture firm (formerly e.ventures) with a New York office, backing consumer and marketplace companies from seed through growth. Portfolio includes Farfetch and Bumble.

Madison digital health seed firm founded 2015 by Mark Bakken. HQ: 551 W Main St, Suite 200, Madison, WI 53703. Invests pre-revenue and early-stage healthcare software/IT.

Indianapolis venture studio and early-stage firm founded in 2015 by Scott Dorsey, Eric Tobias, Mike Fitzgerald, and Kristian Andersen (ExactTarget / Salesforce Marketing Cloud alumni). Creates and funds B2B SaaS companies — co-founding studio companies and investing seed/Series A across enterprise software. Public partner commentary has referenced multiple funds and nearly $400M AUM — verify current figures with the firm.

New York-based multi-stage firm backing ambitious founders in frontier technology from pre-seed through growth, with a global LP network spanning 200+ families and organizations.

Texas’s oldest angel network (founded 2001), a nonprofit connecting accredited investors with early-stage Houston and Texas startups. Member materials cite $100M+ invested across 400+ deals. Typical activity: pre-seed, seed, and Series A across energy, life sciences, healthcare/medtech, software, aerospace/space, and related sectors.

New York hybrid studio and venture fund that co-builds and invests in early-stage consumer and marketplace companies, founded in 2015 by Joe Marchese and partners.

Pre-seed venture firm founded in 2017 by Elizabeth Yin, Eric Bahn, and Shiyan Koh. Writes $150K first checks and backs fast, capital-efficient founders globally.

Chicago-based early-stage firm focused on AI, software, and tech-enabled services with a mid-continent orientation (Midwest, Toronto, Southeast). Invests from idea stage through early Series A for first or second institutional rounds. Known portfolio companies include ShipBob and G2. HQ: 415 N LaSalle Drive, Chicago, IL.

Oklahoma City nonprofit that helps Oklahoma entrepreneurs commercialize technology, access advisory services, and connect to capital — including the independent VC firm Plains Ventures, which i2E spun out in 2019. Has supported 900+ emerging Oklahoma businesses since 1998.

Early-stage investment arm of Invest Detroit, providing capital and ecosystem programs for Michigan high-tech startups. Public materials cite investing since 2009 across 244+ companies with 30 exits, deploying more than $42M through multiple funds and helping leverage billions in follow-on capital. HQ Detroit, MI.

Bellevue, Washington venture firm (Eastside Seattle metro) founded around 2000, historically backing category-creating enterprise software companies with a Seattle–Silicon Valley duo-coast model. Public firm site states existing funds are fully invested; treat as an active legacy PNW franchise managing portfolio rather than an open new-fund checkwriter unless the firm confirms otherwise.

New York consumer venture firm co-founded by Natalie Massenet (Net-a-Porter founder), backing D2C brands and retail technology from pre-seed through growth. Known for SKIMS and Glossier.

Sacramento- and Burlingame-linked seed-stage firm founded in 2016 by Dixon Doll, Jack Crawford, and Eric Ball. Invests in artificial intelligence applied to cybersecurity, digital health, robotics, and enterprise software, often alongside corporate venture and strategic acquirer networks. Maintains Sacramento office presence at 801 K Street (state filing address).

Strategic, not-for-profit investor founded in 1999 to accelerate commercial technology adoption for U.S. national security and intelligence agencies.

International venture firm founded in 1996 with offices in London, San Francisco, and New York, backing founders from seed through growth across software and consumer technology.

SOSV's pioneering biotech accelerator and pre-seed fund in San Francisco, backing scientist-founders in human and planetary health; SOSV rebranded the IndieBio program to SOSV SF and SOSV NY in early 2026 while continuing the same deep-tech investing mandate.

San Francisco seed-stage firm co-founded by Garry Tan and Alexis Ohanian in 2012, backing technical founders from pre-seed through Series A across enterprise, consumer, AI, and infrastructure.

Memphis early-stage venture firm investing in technology and life-science companies across the Mid-South.

Pittsburgh nonprofit venture development organization and early-stage investor serving Southwestern Pennsylvania as the Ben Franklin Technology Partners regional partner. Provides seed capital plus mentoring and resources for software, hardware, robotics, and life-sciences startups. HQ: Nova Tower 2, Two Allegheny Center, Suite 100, Pittsburgh, PA 15212. Public materials cite ~$93M invested across hundreds of companies since the late-1990s seed-fund era.

New York–based global software investor founded in 1995, partnering with high-growth technology and software companies from venture through growth equity and buyouts.

New York venture firm co-founded in 2019 by Alexa von Tobel (LearnVest founder) and Penny Pritzker, backing mission-driven founders at seed and Series A across fintech, health, AI, and defense-adjacent technology.

Jacksonville-based angel investment group (JaxAngels) backing early-stage, revenue-generating startups. Members are North Florida operators across finance, healthcare, SaaS, fintech, and software who pair checks with mentoring and industry introductions.

Chicago early-stage venture firm (founded 2012) investing in fintech, application software, and IT/data infrastructure. Thesis-driven and founder-focused; backed by the founders of Jump Trading. HQ: 600 W Chicago Ave, Suite 625, Chicago, IL, with additional U.S. presence.

Cleveland nonprofit entrepreneur support org with JumpStart Ventures investing arm deploying pre-seed, seed, and Series A into Ohio/Midwest tech startups. HQ: 1974 E. 66th Street, Suite 200, Cleveland, OH 44103. JumpStart Ventures materials cite $14M+ AUM across multiple funds.

Bangalore-based early-stage venture firm founded in 2006, backing Indian founders building consumer internet, SaaS, and deep-tech companies from seed through early growth.

Kansas City–focused early-stage venture firm founded in 2016 by Darcy Howe. Co-invests in pre-seed, seed, and Series A rounds (typically rounds of at least $1M) for B2B tech companies with a strategic connection to Kansas or the western half of Missouri. Firm materials and LinkedIn have cited over $100M AUM — verify current figures. HQ Kansas City, MO.

Angel investor network with active Boise/Idaho chapter alongside Seattle, Portland, Denver, and Salt Lake City. Members collaborate on due diligence and syndicate individual checks — often filling $250K–$2M seed rounds for Treasure Valley software and outdoor-tech companies.

Kentucky seed/early-stage venture firm (keyhorse.vc) investing statewide with offices including Louisville (Story), Lexington, and Covington. Partnership with KYInnovation / KCED; public materials cite hundreds of Kentucky financings.

Menlo Park venture firm founded by Vinod Khosla in 2004, backing ambitious founders in deep tech, AI, climate, healthcare, and frontier technology from seed through growth.

Menlo Park venture firm founded in 1972 on Sand Hill Road, investing in enterprise software, consumer technology, fintech, and climate from seed through growth.

Fort Lauderdale seed-stage venture firm founded in 2015 that backs founders building AI and software applications to modernize outdated business workflows. Public materials emphasize B2B SaaS and vertical AI, with a stated seed preference, roughly $1.5–$3M average investment, and about 4–6 new investments per year. Office listed at 200 East Las Olas Boulevard, Suite 1400, Fort Lauderdale, FL 33301.

Baltimore early-stage venture firm founded in 2022 by Luke Cooper to invest $1M–$4M in Black and Hispanic-led enterprise SaaS and technology companies, with a hybrid model connecting portfolio companies to corporate acquirers.

Nonprofit venture development organization and CDFI for Upstate New York, combining mentorship with InvestLocal seed capital. LP Fund I raised $5.425M (2019); LP Fund II raised $15.775M (2023). Roughly $17M–$19.5M invested across 100+ companies since 2016. Headquartered in Buffalo; serves 36 Upstate counties.

New York and London growth investor founded in 2019, backing hyper-growth consumer and technology companies with enduring customer relationships from Series A through later stages.

New York seed-stage firm founded in 2010 by Ken and Ben Lerer and Eric Hippeau, among NYC's most active pre-seed and seed investors across consumer, B2B software, and media.

Chicago venture firm founded in 2010 by Groupon co-founders Eric Lefkofsky and Brad Keywell. Invests across seed through later stages in disruptive technology companies, with an operator-heavy, hands-on style and deep roots in the Chicago and Midwest startup ecosystem. HQ commonly listed at 600 W Chicago Ave, Chicago, IL.

Richmond founder-support org formerly Lighthouse Labs (founded 2012). 11-week accelerator plus ongoing founder network; HQ 1717 East Cary Street, Richmond, VA 23223.

Global venture firm founded in 2000 with a major New York office, investing from seed through growth in consumer, enterprise software, media, and AI—early backer of Snap, Affirm, and Grubhub.

New York–based investment firm focused on early-stage technology companies in financial services, per our directory; public portfolio details beyond our coverage remain limited.

London-based seed firm within the Phoenix Court Group, backing UK and European founders from pre-seed through seed since 1999.

Detroit early-stage venture firm founded around 2010 by Jonathon Triest and Brett deMarrais. Known for a founder-first, ‘VC without ego’ style and seed/pre-seed checks. Portfolio historically includes companies such as Honey, Product Hunt, and StockX. Multi-fund firm; public commentary has cited Fund V (~$50M) and roughly $250M total AUM — verify on current ADV/firm materials.

Rochester optics, photonics, and imaging accelerator/fund program (NextCorps) helping startups commercialize light-enabled technologies. Flagship Upstate NY deep-tech on-ramp tied to Rochester’s optics cluster.

New York–based firm investing in frontier science and deep tech — AI, biotech, defense, robotics, and space — often at contrarian, long-duration theses.

Seattle-rooted venture firm founded in 1995, investing from incubation/seed through early and Acceleration (Series B/C) stages. HQ at 999 Third Avenue, 34th Floor, Seattle, WA 98104, with a Palo Alto office opened in 2022. Thesis spans applied AI, intelligent applications, infrastructure, and tech-enabled companies across the West Coast and selectively nationwide.

Seattle venture firm founded in 1995, rooted in Pacific Northwest early-stage investing with selective Palo Alto presence. In January 2025 Madrona announced Fund X and Acceleration Fund IV with a combined $770M — targeting roughly 30 pre-seed/seed/Series A companies in Fund X and 12 Series B/C acceleration bets. Known for Amazon and Microsoft ecosystem adjacency and applied-AI company building across Seattle, the PNW, and the West Coast.

Midwest venture firm (Des Moines roots) investing in early-stage technology companies across insurance, fintech, and enterprise software.

University System of Maryland late-seed fund investing $150K–$500K in ventures tied to USM's 12 institutions, research parks, faculty, students, or graduates — co-investing alongside angels and venture firms.

Minneapolis–St. Paul early-stage venture firm (matchstick.vc) investing in pre-seed and seed software companies.

Chicago-based early-stage venture firm founded in 2014, investing in digital technology companies with an unfair advantage in customer acquisition and retention. Closed a $46M second fund in 2019; portfolio includes Acorns, BuiltIn, Chowly, EatStreet, and SpotHero.

Jacksonville early-stage investment firm founded in 2000 that serves as investor and advisor to seed and early-stage technology companies. Led by former Barnett Banks executives; relationship-oriented, long-term capital with medtech and IT application focus.

Memphis-based venture firm focused on life sciences and healthcare innovations in the Mid-South and beyond.

Birmingham early-stage venture firm focused on Care, Workforce Resilience, and Financial Access, investing from pre-seed through Series A.

Multi-stage Menlo Park firm investing in consumer, enterprise, fintech, and healthcare — and manager of the $100M Anthology Fund with Anthropic for AI-native startups.

Houston early-stage venture firm founded ~2005, focused on B2B SaaS and data platforms across Middle America (Texas and Central U.S.). Firm materials cite $750M+ AUM, 275+ companies backed, and offices in Houston, Austin, Detroit/Ann Arbor, and Chicago. Typical focus: seed extension through Series A with operational support; HQ at 3737 Buffalo Speedway, Houston, TX.

Denver venture and growth-equity firm founded in 1998 with Rockies-region roots spanning 40+ years of combined founder experience. Meritage invests $5M–$15M in network-enabled services with recurring revenue ($3M–$20M ARR profile) and runs a FastStart program for earlier-stage bets up to ~$1M.

New York proptech specialist backing software and services across the real estate value chain — construction, operations, insurance, and climate — from pre-seed through Series A.

Michigan’s largest association of regional angel groups and manager of VC funds (MCN Ventures). Headquarters: 37 Ottawa Ave NW, Suite 200, Grand Rapids, MI 49503, with Ann Arbor office in the First National Building (201 S. Main St). Invests early-stage life sciences, advanced manufacturing, and software/tech.

Corporate venture arm of Boise-headquartered Micron Technology. Runs a $300M program investing in early-stage deep tech founders building sustainable compute infrastructure and advanced AI/ML solutions, with strategic support tied to Micron’s semiconductor and memory ecosystem.

Sacramento-region institutional VC dual-headquartered in Sacramento, CA and Austin, TX. Invests in Seed and Series A enterprise software (Software++ thesis: transformational tech plus multi-layered monetization). Founded 2014; publicly cites $360M+ AUM and $1–5M initial checks, often as first institutional investor.

Nashville early-stage venture firm founded in 2002, investing in life sciences, AgTech, and disruptive technology. Hands-on operator model with investments across 60+ companies historically (firm materials). Targets seed and early venture in medical devices, diagnostics, animal health/agriculture tech, and healthcare/business technology.

Early-stage venture firm investing in software, hardware/services, and life-sciences companies across the greater Appalachian region. Offices in Pittsburgh, PA (100 S. Commons, Suite 102) and Morgantown, WV. Co-founded by Mike Green and Matt Harbaugh (Harbaugh formerly CIO at Innovation Works). Targets large seed rounds (~$1–5M company raises) with typical initial checks of $200K–$500K per firm materials.

Omaha pre-seed and seed firm founded in 2022 by Nebraska founders Charlie Cuddy, John Grange, and Manny Quevedo. MOVE Fund I is a $10M vehicle (investing from Jan 2023) focused on capital-efficient software and technology companies built in Nebraska and the Midwest. HQ: 1229 Millwork Avenue, Suite 104, Omaha, NE.

Los Angeles venture firm and startup accelerator (MuckerLab) founded in 2011, investing pre-seed through Series A in internet software and services outside Silicon Valley. Venice HQ at 1631 Electric Avenue; also active in Austin and Toronto.

Austin-based, thesis-driven crypto investor backing tokens, protocols, and companies — known for early Solana ecosystem conviction and public research theses.

Nashville early-stage investment platform founded in 2003 that pairs pooled venture funds with a network of 100+ professional investor partners (often healthcare/tech operators). Manages vehicles including NCN Fund IV (>$70M commitments announced 2022). Focuses on seed/Series A acceleration capital for early-growth companies, frequently with ~$1–3M revenue raising a first institutional round.

Nebraska angel investor network founded in 2006 with 100+ accredited members investing in early-stage, high-growth companies across Nebraska and the Midwest. Members deploy individual capital (not a pooled fund) with syndicated terms; Gust lists the group in Omaha, NE. Public materials cite $75M+ invested across 85+ portfolio companies.

Ali Partovi's San Francisco community and fund backing exceptional technical founders from pre-seed through seed — via Neo Scholars, Neo Residency, and direct investments.

Global multi-stage firm founded in 1977 with a major New York office — investing across technology, healthcare, and life sciences from seed through growth.

New Mexico’s premier angel network (nmangels.com). Nonprofit intermediary since 1999; members have invested $40M+ into 75+ companies. Prefers NM-based companies; offices include Albuquerque (Innovation Parkway) and Santa Fe.

Nonprofit early-stage investor for Greater New Orleans. Requires portfolio HQ in the 10-parish region (Orleans, Jefferson, and listed surrounding parishes). Address commonly listed: 1100 Poydras St Ste 3475, New Orleans, LA.

Newark, NJ–based B2B software fund with corporate backing from Audible/Amazon — investing in vertical AI and enterprise software across the NYC metro.

Austin venture firm founded in 2015, backing bold entrepreneurs in 'Next Coast' markets outside traditional coastal hubs. Thematic seed through Series B investing in software, healthcare, and IT — with a venture partner network and operator-built platform for portfolio support.

Des Moines / Iowa early-stage venture firm investing in Midwest technology companies including insurtech and enterprise software.

Seed-only, high-conviction firm investing in the 'everyday economy' — software and AI for mass-market consumer and business problems — from bicoastal offices including NYC.

Corporate venture arm of Northwestern Mutual investing in FinTech, WealthTech, Health & Wellness, and data analytics startups. Parent mutual is Milwaukee-headquartered; Future Ventures also partners with gener8tor on Milwaukee-focused programs.

Palo Alto multi-stage firm investing across consumer, enterprise, healthcare, and fintech from seed through growth equity — backed by long-duration Wells Fargo capital.

Brooklyn pre-seed firm writing first checks to technical, product-obsessed founders in NYC — often the earliest institutional capital in a round.

Coral Gables / Miami early-stage VC founded in 2017 by operators Kristy King, Salo Sredni (Paymentwall founder), and David Zinn. Ocean Azul backs B2B software and deep-tech companies using applied AI, robotics, and connectivity — with U.S. and Israel deal flow and a preference for Florida-based teams when thesis fits.

Portland-based venture firm investing in Oregon and Pacific Northwest technology companies from seed through growth. Appears as co-investor on national deals while remaining an Oregon HQ firm.

Chicago-headquartered early-stage firm (founded 1999) that leads Seed and Series A rounds in AI infrastructure, AI-native software, and frontier tech transforming productivity and automation. Long Midwest roots with a coast-to-coast investor network; SEC Form D filings list 549 W. Randolph Street, Chicago, IL as principal place of business.

Atlanta inception-through-seed venture firm investing in founders building across the Southeast. Co-founded in 2020 by Michael Cohn (Cloud Sherpas / Techstars Atlanta) and Sean O’Brien; HQ commonly listed at 311 Nelson Street SW, Suite 16077, Atlanta, GA 30308. Generalist early checks; firm site states first checks of $250K–$1.5M and preference to lead or co-lead.

Washington, D.C. multi-stage venture firm founded in 2001, specializing in cybersecurity and dual-use deep tech for commercial and government markets. HQ at 2000 K St NW; also offices in New York, Silicon Valley, London, and Luxembourg.

Research Triangle life-science investment firm (pappas-capital.com) backing biotech and healthcare companies connected to the Triangle ecosystem.

Menlo Park pre-seed and seed firm partnering with founders via direct seed rounds and the PearX accelerator — enterprise, health, consumer, and deep tech.

Dallas early-stage venture firm founded in 2014 by Ross Perot Jr. and Anurag Jain. Partners with technology founders building disruptive B2B companies; public materials cite themes spanning healthcare services/tech, supply chain, real estate/proptech adjacency, and government/defense. HQ Dallas, TX. Website: perotjain.com.

Phoenix member-led angel network focused on software startups with early sales traction — typically $100K ARR signals — backing primarily Phoenix-based B2B companies alongside PHX FWD ecosystem partners.

Phoenix seed-stage venture firm founded by Gregg Scoresby, leading or co-leading $1M–$5M rounds in high-growth Arizona B2B software companies — second fund closed at $25.4M in commitments (August 2023).

Seattle startup studio and venture platform founded in 2015, operating PSL Studio (company creation from scratch) and PSL Ventures (pre-seed and seed fund for external and studio-born startups). PSL Ventures II closed at $100M in 2023; Studio III closed at $20M. The firm reports ~$180M through PSL Ventures and has spun out 33+ venture-backed companies from its Seattle lab.

Oklahoma City seed and Series A firm investing in entrepreneurs between the coasts. HQ listed at 840 Research Parkway, Oklahoma City, OK.

Berlin-based early-stage firm investing $1–10M in B2B SaaS, marketplaces, and AI across Europe and globally. Known for thesis-driven bets like Revolut, Loom, and Attio.

Portland early-stage fund investing in Oregon startups at pre-seed and seed.

NYC-focused seed firm with a hands-on portfolio impact team. Raised $625M Fund V in 2026 — the largest NYC-exclusive seed vehicle — and backed companies including Chief and Latch.

gener8tor-powered 12-week in-person healthtech accelerator in Birmingham. Published program terms include $50k for 5% common stock, with optional additional capital that can bring total investment up to roughly $90k; cohorts relocate to Birmingham for the program.

Omaha venture fund (Burlington Capital family) investing in Nebraska post-revenue and growth-stage companies with a founder-friendly debt-equity / revenue-aligned model aimed at profitability over hyper-dilutive growth. Public address: 1004 Farnam Street, Suite 400, Omaha, NE.

Jacksonville, Florida early-stage venture firm investing in software and technology companies across the Southeast and beyond.

Cincinnati-rooted early-stage investor network formerly Queen City Angels (founded 2000); rebranded to QCA Ventures in February 2026. 219+ accredited members across 25 states; public materials cite $130M+ direct investment into 123+ companies. Focus: life sciences, B2B SaaS, advanced materials, advanced manufacturing.

Nasdaq-listed business development company (ticker: RAND) based in Buffalo. Provides higher-yielding debt with equity kickers to lower middle-market companies (typical targets around $10M revenue and $1.5M+ EBITDA). Portfolio fair value was about $48.5M across 20 companies at year-end 2025. Not a classic seed VC — growth and debt-focused. Early historical investor in ACV Auctions.

Denver early-stage venture firm (range.vc) founded in 2020 by operators Adam Burrows and Chris Erickson. Focuses on pre-seed and seed investments, historically with a strong Colorado Front Range emphasis and a thesis around founders with hard-won, hard-to-replicate insights in overlooked categories. Press reported a ~$39M Range Fund II close in 2024 for Colorado-focused deployment.

Multi-stage venture firm with offices in New York and Silicon Valley, investing from seed through growth in AI, enterprise SaaS, infrastructure, and developer tools. Early bets include Netflix, Stripe, and Snowflake.

Louisville-based early-stage venture firm investing across the Midwest and South 'heartland and commerce corridor' — pre-seed and seed checks of roughly $750K–$1.25M, often first institutional capital for CPG, B2B SaaS, health, and supply-chain founders.

Reno, Nevada early-stage fund investing in Northern Nevada and Sierra-region startups at seed.

Columbus venture studio / public-private seed platform providing capital, mentoring, and space. Downtown hub: Rev1 at The Peninsula, 330 Rush Alley Suite 100, Columbus, OH 43215; Rev1 Labs at 1275 Kinnear Rd, Columbus, OH 43212.

Washington, D.C. investment firm founded in 2005 by Steve Case, operating Revolution Ventures (early-stage tech), Revolution Growth (later-stage consumer), and the Rise of the Rest Seed Fund for companies outside coastal hubs. HQ at 1717 Rhode Island Ave NW.

Charlotte venture fund focused on post-revenue fintech and insurtech startups, often tied to the RevTech Labs accelerator pipeline. Average investments cited at roughly $200K–$400K; strategic partner to RevTech Labs Foundation programs in the Queen City banking corridor.

Providence growth investor evolved from Betaspring accelerator. Provides non-dilutive / revenue-based capital to early revenue companies. HQ: 91 Clemence Street, Providence, RI 02903; also lists Boston.

Global fintech-focused investor founded in 2012. Early bets include Coinbase, Robinhood, and Revolut; the firm has backed 170+ companies across payments, banking, and crypto infrastructure.

Memphis-headquartered early-stage venture firm investing in applied AI, advanced computing, hardware, and automation for manufacturing, logistics, energy, and defense buyers. Fund II closed oversubscribed at over $180M (Dec 2025) with Fortune 500 LPs including FedEx and Cisco Investments.

Albuquerque deep-tech venture studio that co-founds and invests in hard-science companies (advanced energy, robotics, precision manufacturing, quantum) with national-lab adjacency. Selected to lead New Mexico’s $25M quantum commercialization initiative.

Accredited angel group investing in early-stage, high-growth Upstate New York startups. Formed 2005; 60+ members investing via funds and direct checks. Applications via [email protected] / rochesterangels.com.

Portland and Lake Oswego early-stage venture firm founded in 2010, investing seed and Series A across software, healthcare, and SaaS — with a stated focus on undercapitalized markets and Pacific Northwest deal flow.

One of NYC's longest-running venture firms, founded in 1994. Multi-stage investor across fintech, enterprise SaaS, marketplaces, and consumer with 400+ portfolio companies.

Sacramento-region angel network funding early-stage Northern California companies outside the core Bay Area HQ cluster — govtech, enterprise, and Capital Region founders.

Boise, Idaho growth-capital firm providing revenue-based / non-dilutive funding to companies that do not fit traditional bank or equity models. Manages Sage Growth Capital Fund I, II, and III from 800 West Main Street, Suite 1460, Boise. Founded in 2019 by Denise Dunlap, Molly Otter, and Kevin Learned.

Santa Barbara–based early-stage venture firm investing in technology companies tied to the Central Coast / UCSB innovation corridor.

Foster City-based firm backing early-in-revenue enterprise SaaS and AI companies from seed through Series B+, with a focus on founder-led growth to repeatable go-to-market.

Santa Barbara early-stage venture firm (founded 2018) investing $500K–$3.5M in B2B SaaS and AI companies with early product-market fit. Team includes DoubleClick founder Kevin O'Connor; AppFolio and Procore alumni among advisors.

Early-stage firm backing dual-use and frontier-tech founders from the military, intelligence community, and national labs. Leads seed rounds with $2–5M checks in AI, robotics, space, and defense tech.

Helps daring founders build legendary companies from idea to IPO and beyond. Multi-decade firm backing category-defining companies including Apple, Google, Stripe, and Airbnb.

Northern Nevada / Tahoe-region angel network investing in early-stage companies across the Sierra corridor including Reno–Tahoe.

Providence evergreen nonprofit seed fund supporting Rhode Island early-stage technology ventures (founded 1997). Addresses historically include 3 Davol Square and 225 Dyer St, Providence, RI. Often works with Brown and URI commercialization teams.

Early-stage firm with offices in San Francisco, New York, Boston, and beyond, backing founders across consumer, enterprise, crypto, and the creator economy.

SoftBank Group’s dedicated Latin America technology investment platform, with a Miami investment team base at 600 Brickell Avenue. SoftBank announced the US$5 billion SoftBank Latin America Fund in 2019 and a US$3 billion initial commitment to SoftBank Latin America Fund II in 2021. Invests across technology-enabled companies in the region — historically spanning e-commerce, digital financial services, healthcare, education, enterprise software, and related internet-economy categories — from early venture through later stages.

Female-led millennial venture firm investing in diverse founders globally, with a focus on inclusion in venture capital. Portfolio spans consumer, health, and AI companies led by underrepresented founders.

Leading venture firm with offices in New York and Boston, known for early bets on Twitter, Slack, Discord, and Coinbase. Invests across consumer and enterprise technology from seed through growth.

Boise-based early-stage venture firm (also branded Stage Global Partners) that leads seed financings and milestone investments through Series A and B. Relocated from Seattle to Boise around 2019; co-invests frequently with Capital Eleven on Treasure Valley deals such as OurPetPolicy (Series A, Jan 2026).

Miami-based venture firm founded in 2017 that invests across stages in companies built on breakthrough science and technology. Public thesis language emphasizes energy transition, industrial biology, space infrastructure, and next-generation platforms. HQ commonly listed at 2666 Brickell Avenue, 3rd Floor, Miami, FL 33129; Form D filings use the same Brickell address.

Seed-stage firm in San Francisco investing in founders building durable moats in enterprise, fintech, and health. Known for concentrated seed bets with heavy follow-on reserves.

Tampa Bay 501(c)(3) nonprofit startup accelerator (founded 2008) supporting tech founders with zero-equity accelerator programs, mentorship, and investor connections. HQ at 501 E Kennedy Blvd, Suite 650, Tampa, FL; St. Pete presence at Thrive DTSP.

Jacksonville, Florida venture studio that partners with founders on zero-to-one companies — providing operations, go-to-market systems, and capital formation rather than only writing a late check. Active across AI, deep tech, workforce/edtech, and related category-creating products.