St. Louis city hub: 7 funds and 3 startups matched from our directory. Agtech, plant science, and biotech around Corteva/Bayer corridor.
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MO · Midwest

St. Louis venture capital & startups

St. Louis agtech and biotech — BioGenerator, Cultivation Capital, Geneoscopy, CoverCress, Allotera.

St. Louis markets plant science and biotech around the Bayer Crop Science corridor and WashU/Cortex: CoverCress (Bayer majority stake), Geneoscopy ($105M Series C for ColoSense), and Allotera Therapeutics (formerly Wugen) for allogeneic CAR-T. Local formation and early capital: BioGenerator Ventures and Cultivation Capital. National ag/climate comps remain category context — not fake STL HQs.

Funds matched

7

Startups matched

3

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Aliases: st. louis, saint louis, st louis. Curated startups only with clear public STL association. Do not reassign Bay Area or Austin companies.

Venture firms in St. Louis

Matched from fund headquarters in our directory (alias-based). Dual-HQ firms may appear in more than one city.

Firm HQ (directory) Leads
BioGenerator Ventures St. Louis, MO Pre-Seed, Seed
Cultivation Capital St. Louis, MO Seed, Series A
Khosla Ventures Menlo Park, CA Seed, Series A
ARCH Venture Partners Chicago, IL Seed, Series A
F-Prime Capital Cambridge, MA Series A, Series B+
Lux Capital 888 7th Ave, New York, NY 10106 Seed, Series A
General Catalyst Cambridge, MA Series A, Series B+

Startups we cover in St. Louis

Matched from startup hq fields. Many profiles still lack HQ — curated lists in editorial notes fill gaps when verified.

Startup One-liner HQ
Geneoscopy GI diagnostics company — noninvasive colorectal cancer screening (ColoSense) and related tests. St. Louis, MO
CoverCress Gene-edited winter oilseed (pennycress) crop for low-carbon fuel feedstock and cover-crop benefits. St. Louis, MO
Allotera Therapeutics Clinical-stage allogeneic (off-the-shelf) CAR-T company for T-cell malignancies — formerly Wugen. St. Louis, MO

Coverage gaps

  • Benson Hill and additional plant-science companies

    CoverCress is covered; more STL agtech profiles still needed for a full shortlist.

  • Broader BioGenerator / STL VentureWorks portfolio density

    Primary local formation path — more portfolio company pages still missing.

  • Additional medical-device spinouts from WashU / Cortex

    Secondary STL thesis beyond ag and the few clinical biotech pages we cover.

Related reading

St. Louis FAQs

Practical answers for founders researching this investor.

BioGenerator Ventures and Cultivation Capital are the local HQ pages. Agtech and bio founders also shortlist national climate/bio firms (e.g. Khosla, ARCH) from /directory.
Geneoscopy, CoverCress, and Allotera Therapeutics (formerly Wugen). Related reading may still link national ag comps (e.g. Granular) with explicit non-STL HQ labels.
Anchor on plant-science or biotech proof, use BioGenerator/Cultivation for formation and seed, then shortlist thesis-fit national funds via /vc/st-louis and /directory.
Seed and company-creation capital (BioGenerator pathways) are the local strength. Growth equity for STL companies typically comes from national agtech, diagnostics, and biotech specialists (e.g. Geneoscopy’s Bio-Rad–led Series C).