F-Prime Capital
Cambridge-based venture firm affiliated with Fidelity Investments, with a heritage tracing to Fidelity's venture arm. Self-capitalized investor in life sciences, healthtech, enterprise software, fintech, and frontier technology across North America and Europe.
Typical check size
$1M-$10M (stage-based estimate)
Founded
2016
Headquarters
Cambridge, MA
AUM
N/A
Rounds they lead
Series A
Series B+
Rounds they invest
Seed
Series A
Series B+
Portfolio companies we track
Startups in our directory that list F-Prime Capital as an investor (6 total).
- BioAge Labs Clinical-stage biotech targeting metabolic disease and aging biology (public: BIOA).
- Firefly Health Virtual-first primary care and employer health-plan platform.
- Method Embedded API linking consumer debt accounts for repayment and balance transfers.
- Nava Therapeutics Biotech developing next-generation lipid nanoparticle (LNP) delivery systems.
- PatientPing National ADT care-coordination network, now part of Bamboo Health after Appriss Health acquisition.
- Zus Health Shared health data platform giving digital health builders a common patient record (ZAP).
Related investment articles
FAQs about F-Prime Capital
Stage fit, check size, thesis, and how founders typically approach this firm — based on public sources and our directory.
Per our directory, F-Prime Capital leads Series A and later rounds and participates from seed onward. The firm is early-stage by preference but publicly describes itself as stage-agnostic for exceptional teams.
F-Prime does not publish one fixed check. Its website cites $5.3B+ under management with capacity from seed through growth; third-party profiles and the firm's own materials describe wide flexibility by stage rather than a single standard ticket.
F-Prime Capital is headquartered in Cambridge, Massachusetts, with offices in London and San Francisco. It invests across the Americas and Europe in healthcare and technology.
Our directory tags healthtech and biotech-life-sciences. F-Prime publicly invests in life sciences (therapeutics, medtech), healthtech services, enterprise software, fintech, frontier tech, and crypto—often favoring clear regulatory pathways in healthcare.
F-Prime frequently leads or co-leads seed and Series A rounds, especially in healthcare and technology, and participates in later follow-ons for portfolio winners given its self-capitalized structure.
Startups in our directory with F-Prime Capital listed include Firefly Health (/startup/firefly-health), Zus Health (/startup/zus-health), PatientPing (/startup/patientping), BioAge Labs (/startup/bioage-labs), and Nava Therapeutics (/startup/nava-therapeutics).
Founders can reach the team through fprimecapital.com. Warm intros from scientists, clinicians, or prior portfolio founders help in healthcare; we do not list individual partner inboxes.
We do not yet have a dedicated F-Prime fund article. Our digital-health and biotech industry hubs reference healthcare investors active in overlapping sectors.