· Updated · Venture Capital Tracker · investment-strategies  · 4 min read

Jacksonville Startups and VC Firms in 2026: Health-IT, Fintech, and North Florida Capital

Jacksonville’s venture map in 2026 — Availity, Finxact’s Fiserv exit, Forcura/Mosai, NLP Logix, Hazlnut, PS27 Ventures, Mayport, and Chang Robotics Fund — distinct from Miami’s LatAm gateway.

Jacksonville Startups and VC Firms in 2026: Health-IT, Fintech, and North Florida Capital

Jacksonville is North Florida’s ports, insurance, health-IT, and fintech infrastructure corridor — not Miami’s LatAm gateway. Mayo Clinic, Baptist Health, FIS, and JAXPORT create buyer density for software founders even when Series A capital still comes from elsewhere.

This guide covers the companies and investors we actually profile — not a padded “top 50” list.

City hub: /vc/jacksonville · All cities: /cities · Fund directory: /directory · Miami contrast: /vc/miami

What Jacksonville is (and is not)

Jacksonville is…Jacksonville is not…
Availity payer-provider network scale + Finxact core-banking exitMiami LatAm fintech / crypto gateway
Forcura → Mosai post-acute workflow + NLP Logix enterprise AIA dense JAX multi-stage VC HQ market
Local seed via PS27, Mayport, Chang Robotics FundA dump of South Florida companies for Florida SEO
Hazlnut hospitality SaaS with JAX HQClearsense (relocated HQ to Nashville, Feb 2025)

Startups we cover in Jacksonville

CompanyWhat they doStage / statusNotable capitalProfile
AvailityHealthcare information network for eligibility, claims, clinical exchangeGrowth / privateScaled health-IT infrastructure/startup/availity
FinxactCloud-native core banking / embedded finance (Fiserv subsidiary)Acquired (Fiserv, Apr 2022, ~$650M)Georgian, Live Oak pre-exit/startup/finxact
ForcuraPost-acute care workflow software (rebranded Mosai post-merger)Growth / PE-backedBerkshire Partners lead (Mar 2025, ~$1B reported)/startup/forcura
NLP LogixEnterprise AI/ML deployment for healthcare, finance, logisticsGrowth / private11k sq ft HQ expansion (Jan 2024)/startup/nlp-logix
HazlnutRestaurant digital menu and QR ordering platformSeed / privateHospitality SaaS/startup/hazlnut

Why these names matter

Availity is still the density anchor — real revenue-scale clearinghouse/network that every Florida payer-provider software founder eventually hits.

Finxact is the fintech comps slide: API-first core banking built in Jacksonville, sold to Fiserv for ~$650M (April 2022). If you are selling into banks or embedded finance, that exit is the proof North Florida ships bank-grade software.

Forcura shows post-acute healthtech scale: a 2012 JAX founding grew to a March 2025 merger with Medalogix under Berkshire Partners (press reported ~$1B). The combined platform rebranded as Mosai (Oct 2025) with dual HQ in Jacksonville and Nashville.

NLP Logix is operator-grade AI — custom ML deployed into regulated buyers, not a pitch-deck LLM wrapper. The January 2024 Southside HQ expansion signals hiring intent.

Hazlnut is the hospitality wedge: QR menus and ordering for operators — concrete Florida restaurant software.

Local investors (Jacksonville HQ or program)

FirmRoleStagesProfile
PS27 VenturesEarly-stage software / fintech / healthtech (Southeast + beyond)Pre-seed – Series A/fund/ps27-ventures
Mayport Venture PartnersRelationship-oriented seed / early-stage advisor-investorPre-seed – Seed/fund/mayport-venture-partners
Chang Robotics FundManufacturing-tech / robotics (founded 2024)Pre-seed – Seed/fund/chang-robotics-fund

How to read this table: PS27 is the most active institutional seed name. Mayport is long-horizon, relationship capital (former Barnett Banks leadership). Chang Robotics Fund is newer — manufacturing and robotics aligned with port/industrial buyers.

JAX Hub (Paysafe + UNF fintech accelerator, launched Nov 2025) is a formation program — not a classic VC fund in our directory. Founders still use it for pilots and intros.

National capital Jacksonville founders still need

FirmWhy Jacksonville founders careProfile
Bessemer Venture PartnersCloud/SaaS, healthtech roadmaps/fund/bessemer-venture-partners
Insight PartnersGrowth-stage software scale/fund/insight-partners
General CatalystMulti-stage enterprise / fintech/fund/general-catalyst

Local seed vs national Series A — what differs

PS27 / Mayport / Chang seedNational Series A+
Best forFirst checks, North Florida buyer pilotsScaling health-IT, fintech, or hospitality software nationally
What they underwriteTeam + JAX operator accessCategory, retention, and ownership math
Mistake to avoidPadding decks with Miami LatAm compsWaiting for a JAX growth-GP HQ that does not exist

Worked example (illustrative)

Setup: A Jacksonville health-IT workflow startup closes $750k with PS27 Ventures and lands two regional payer logos through Availity-adjacent workflows.

Move: Eighteen months later ARR hits ~$1.4M with a named health-system pilot; they raise a $12–15M Series A from a national digital-health firm.

Punch: The diligence artifact was operator KPIs and payer connectivity, not “Florida startup.” Keep Miami out of the comps unless your product is cross-border fintech.

When Jacksonville is the wrong capital market

  • You are building LatAm remittance or crypto — use /vc/miami.
  • You cite Clearsense as a current JAX HQ comp — it relocated to Nashville (Feb 2025).
  • You invent port/logistics /startup/ URLs we still list as coverage gaps.
  • You refuse national meetings for Series A while expecting growth-GP terms locally.

How to use this page

  1. Read company pages: Availity, Finxact, Forcura, NLP Logix, Hazlnut.
  2. Shortlist local funds: PS27, Mayport, Chang Robotics.
  3. For Series A+, add national rows above from /directory.
  4. Track live matches on /vc/jacksonville. Compare Florida depth via Miami VC firms 2026.

Sources

  1. Company and fund profiles linked above (Venture Capital Tracker JSON)
  2. Fiserv / Finxact acquisition (Apr 2022, ~$650M)
  3. Forcura / Medalogix merger PR (Mar 2025); Mosai rebrand (Oct 2025)
  4. NLP Logix HQ expansion (Jan 2024, Jacksonville Business Journal)
  5. JAX Hub launch (Nov 2025, L Marks / Paysafe / UNF)
  6. PS27 Ventures firm materials; Mayport Venture Partners (mayport.cc)

By Venture Capital Tracker

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Editorial note: AI tools assisted with research, structure, or drafting. Venture Capital Tracker retains human editorial responsibility for factual accuracy, relevance, and source quality before publication.

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