San Antonio city hub: 7 funds and 4 startups matched from our directory. Cyber (military), healthcare, and Texas enterprise.

TX · South

San Antonio venture capital & startups

San Antonio cyber (military), robotics, and healthcare access — Active Capital, Alamo Angels, and SA HQ startups we cover.

San Antonio’s differentiated thesis is military-adjacent cybersecurity (JBSA / NSA Texas gravity), logistics robotics, and healthcare access tech. We cover Active Capital and Alamo Angels locally, plus startups Darkhive, Plus One Robotics, Insane Cyber, and SafeRide Health.

Funds matched

7

Startups matched

4

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All funds

Alias: san antonio. Curate only with clear public San Antonio association. Do not pull Austin cyber/defense names without dual evidence.

Venture firms in San Antonio

Matched from fund headquarters in our directory (alias-based). Dual-HQ firms may appear in more than one city.

Firm HQ (directory) Leads
Active Capital San Antonio, TX Pre-Seed, Seed
Alamo Angels San Antonio, TX Seed
In-Q-Tel Arlington, VA Series A, Series B+
Lux Capital 888 7th Ave, New York, NY 10106 Seed, Series A
Founders Fund New York, NY Series A, Series B+
8VC Austin, TX Seed, Series A
Bessemer Venture Partners New York, NY Seed, Series A, Series B+

Startups we cover in San Antonio

Matched from startup hq fields. Many profiles still lack HQ — curated lists in editorial notes fill gaps when verified.

Startup One-liner HQ
Darkhive U.S.-made autonomous uncrewed aircraft systems and secure edge software for defense and public safety. San Antonio, TX
Plus One Robotics AI vision software and supervised-autonomy robots for high-speed parcel picking and depalletizing. San Antonio, TX
Insane Cyber Automated OT/ICS cybersecurity — monitoring, threat hunting, and incident response for critical infrastructure. San Antonio, TX
SafeRide Health Technology-first non-emergency medical transportation (NEMT) platform for Medicaid, Medicare Advantage, and providers. San Antonio, TX

Coverage gaps

  • Additional JBSA / NSA Texas–adjacent cybersecurity startups

    Primary SA search intent; more verified HQ + investor profiles still needed beyond Darkhive and Insane Cyber

  • Rackspace-era enterprise cloud alumni companies

    Historic SA enterprise software gravity; not fully mapped as venture profiles here

  • Broader SA healthcare IT beyond NEMT

    Secondary metro thesis; SafeRide is covered — more payer-provider tools remain gaps

Related reading

San Antonio FAQs

Practical answers for founders researching this investor.

Directory SA-linked firms include Active Capital (/fund/active-capital) for pre-seed enterprise/AI and Alamo Angels (/fund/alamo-angels) for seed syndication. Cyber and robotics founders also shortlist national security/enterprise investors from /directory. Hub: /vc/san-antonio.
Darkhive (defense UAS), Plus One Robotics (parcel robotics), Insane Cyber (OT security), and SafeRide Health (NEMT). See /vc/san-antonio.
Lead with clearances, DoD/commercial dual-use traction, robotics deployment metrics, or healthcare buyer proof. Start with Active Capital / Alamo Angels for early checks, then stage-match national funds in /directory. Do not borrow Austin defense HQs without dual-city evidence.
Seed and SBIR/contract-led paths are strong locally (Alamo Angels, Active Capital, DoD awards). Growth rounds for SA cyber/robotics usually still need national specialists once revenue or contracts clear — Darkhive’s RTX-led Series B is the template.