Startup profile for Periodic Labs: latest funding, latest known valuation, total disclosed funding, investors, status, sources, and why the company is interesting. Part of the Venture Capital Tracker startup directory.
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Periodic Labs funding, valuation and investors

AI-native autonomous lab accelerating materials science via robotic experimentation.

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Funding, valuation & investors

Answer-first snapshot

Latest funding

Seed

$300M · September 2025

Latest known valuation

Not publicly disclosed

Total disclosed equity funding

$300M

Excludes debt, grants, acquisitions, secondaries, and IPO proceeds.

Current status

private

seed · San Francisco, CA

Investors in latest funding

Lead: Andreessen Horowitz

Sources: latest funding Last verified: 2026-07-25

Overview

Periodic Labs emerged from stealth in September 2025 with a $300M seed led by Andreessen Horowitz to build AI scientists and autonomous physical laboratories for materials discovery. Co-founders Liam Fedus (ex-OpenAI, ChatGPT co-creator) and Ekin Dogus Cubuk (ex-DeepMind materials lead, GNoME project) pair LLM hypothesis generation with robotic wet labs. Initial focus includes superconductors and semiconductor heat dissipation.

Why Periodic Labs is interesting

Largest seed of 2025; pairs LLM hypothesis generation with automated physical lab loops.

Product & use cases

Autonomous labs where AI agents design experiments, robots synthesize materials, and feedback loops train models on unique physical-world data.

  • Materials discovery for semiconductors
  • Superconductor research automation
  • Defense and space R&D acceleration

Key facts

  • a16z portfolio status: Active
  • Seed (2025): $300M led by a16z for AI scientist autonomous lab (TechCrunch / a16z)
  • Co-founders: Liam Fedus (OpenAI/ChatGPT) and Ekin Dogus Cubuk (Google Brain materials)
  • Co-investors: no additional institutional investors disclosed in public sources reviewed 2026-07-24

Funding history (newest first)

Seed

2025-09 $300M

Source: https://techcrunch.com/2025/09/30/former-openai-and-deepmind-researchers-raise-whopping-300m-seed-to-automate-science/

Investors in our directory

Funds linked from Periodic Labs's profile — open a fund page for stage focus and related deal articles.

Andreessen Horowitz

Competitive landscape

Edge: Closed loop of physical experiments generating proprietary data unavailable from internet-trained models alone.

Periodic bets physical-world data moats beat pure simulation. Capital intensity and eval rigor are key risks.

  • Chemical.ai adjacent

    AI for chemistry discovery.

  • Radical AI labs adjacent

    Autonomous science startups.

  • Internal pharma R&D incumbent

    Manual lab workflows; slower iteration.

Notable stories

  • Largest seed round of 2025 per TechCrunch — Fedus and Cubuk merged OpenAI agent work with DeepMind materials science.

Industries

Deep Tech AI & Machine Learning Robotics

Related funding articles

Venture Capital Tracker pieces that cover Periodic Labs's financing or category context.

FAQs about Periodic Labs

Practical answers founders, operators, and investors typically search for.

AI scientists plus autonomous labs for physical materials discovery.
Liam Fedus (ex-OpenAI) and Ekin Dogus Cubuk (ex-DeepMind).
$300M seed led by a16z. See /fund/andreessen-horowitz.
Superconductors and semiconductor materials per company blog.
Periodic focuses on physical lab automation, not general LLMs.
NVentures, Felicis, Accel, Bezos and Schmidt as angels per press.
September 2025.
No — B2B R&D for semiconductors, defense, space.
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Editorial note: AI tools assisted with research, structure, or drafting. Venture Capital Tracker retains human editorial responsibility for factual accuracy, relevance, and source quality before publication.