Startup profile for Fathom Therapeutics: latest funding, latest known valuation, total disclosed funding, investors, status, sources, and why the company is interesting. Part of the Venture Capital Tracker startup directory.

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Fathom Therapeutics funding, valuation and investors

New York preclinical drug-discovery company combining protein-motion simulations, quantum chemistry and AI to design small-molecule therapies.

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Funding, valuation & investors

Answer-first snapshot

Latest funding

Series A (cumulative; original $47M announced April 27, expanded to $55M by May)

$55M · May 2026

Latest known valuation

Undisclosed

Series A (cumulative; original $47M announced April 27, expanded to $55M by May) · May 2026

Total disclosed equity funding

$55M

Excludes debt, grants, acquisitions, secondaries, and IPO proceeds.

Current status

private

series a · New York, NY, USA (also Boston)

Investors in latest funding

Lead: Sutter Hill Ventures

Other: Lilly Ventures , Chemistry , Alexandria Venture Investments , Empire State Development NY Ventures , Kos BioVentures (Kos Biotechnology Partners)

Sources: latest funding · prnewswire.com Last verified: 2026-11-09

Overview

Fathom Therapeutics (formerly Atommap Corp.) is a New York-headquartered preclinical biotechnology company with a Boston office, founded by Huafeng Xu (CEO), Yujie Wu (CTO) and Jesús Izaguirre (Chief Computational Scientist). Its Microcosmos platform uses computational physics, quantum chemistry and machine learning to simulate molecular/protein motions and guide small-molecule design.

Its commercial model combines internal drug programs and external discovery partnerships, not a publicly priced self-serve SaaS tool.

FINANCING CHRONOLOGY AND NOVEMBER FALSE-FRESHNESS TRAP: The company-issued April 27, 2026 PR Newswire release announced an oversubscribed $47 million Series A, led by Sutter Hill Ventures, with Chemistry, Alexandria Venture Investments and NY Ventures.

On October 29 the company retrospectively said its Series A financing reached $55 million in MAY 2026, with Lilly Ventures also participating; the exact May closing date and the mechanics/timing of the $8M increase from the April disclosure were not specified. On November 6, Kos Biotechnology Partners disclosed its participation through Kos BioVentures in THAT SAME $55M round.

This DOES NOT establish another $55M in November, nor that Kos independently invested $55M. Kos's own cheque and Fathom's valuation are undisclosed. The $55M is the later total Series A figure; do not add $47M to it. No separate additional Series A close or seed round is fabricated.

SCIENTIFIC PRODUCT AND BUYER TOUR (illustrative; not hands-on verification): (1) A pharmaceutical discovery team specifies a disease-linked protein target and known molecular or assay data. (2) Fathom's scientists use Microcosmos to model conformational motion and transient cavities rather than relying on a single static crystal structure. (3) Candidate small molecules are designed or optimized against simulated target states.

(4) Wet-lab assays test potency, selectivity, cellular activity and liabilities, feeding results into iterative design. (5) Promising compounds enter animal efficacy and ADME/toxicology gates; IND-enabling work and clinical testing would be required before efficacy in humans can be claimed. Commercial collaboration economics, IP allocations, milestones and platform license fees are not publicly disclosed. This description is grounded in company statements, not a public product demo.

The original April release says the platform had generated candidates for a challenging target within six weeks and that a lead program was in animal efficacy studies. Fathom describes up to 10,000x faster protein-dynamics modeling versus unspecified baselines; this vendor figure is not a peer-reviewed head-to-head and says nothing by itself about clinical efficacy.

The company's 2026 BIO convention profile reports 12 discovery partnerships since founding and preclinical development, but these are issuer-provided figures, not audited paid-customer counts. The October 29 release introduced Bret Williams as Chief Scientific Officer to translate computational hits into therapeutic programs; this is a scientific development stage, not an approved drug or confirmed clinical benefit.

Comparisons with Schrödinger, Relay Therapeutics and QSimulate should distinguish simulation tools, development pipelines and partnerships.

Primary source 1 (original Apr $47M): https://www.prnewswire.com/news-releases/fathom-therapeutics-formerly-atommap-raises-47-million-in-oversubscribed-series-a-financing-to-translate-physics-and-ai-enabled-small-molecule-design-into-next-generation-medicines-302754272.html Primary source 2 (company's explicit May $55M): https://www.prnewswire.com/news-releases/fathom-therapeutics-appoints-bret-williams-as-chief-scientific-officer-to-translate-microcosmos-insights-into-a-therapeutic-portfolio-302923780.html Primary source 3 (Nov Kos participation, not new close): https://www.prnewswire.com/news-releases/kos-biotechnology-partners-announces-investment-in-fathom-therapeutics-to-advance-novel-ai-driven-drug-discovery-platform-302931959.html 2026 BIO meeting issuer profile: https://convention.bio.org/2026-sessions-and-courses/fathom-therapeutics-inc

Why Fathom Therapeutics is interesting

A November 6 Kos Biotechnology Partners release resurfaced Fathom's already-completed $55M May 2026 Series A, which had been publicly reported at $47M in April. The newer investor announcement is not a new $55M round. Fathom's Microcosmos work targets dynamic protein conformations that static-structure drug design can miss.

Product & use cases

For a pharma discovery buyer: choose a protein target whose motion matters; share available structure/assay context and negotiate a research partnership; model dynamic protein conformations with Microcosmos; iteratively propose molecules and test them in biochemical/cellular wet-lab assays; validate lead candidates in animal efficacy and toxicology before any human trial. This is an illustrative diligence workflow, not a first-person test or claimed public API. Contract prices, milestones, ownership and license terms are undisclosed.

  • Design and optimize small molecules for difficult dynamic protein targets.
  • Preclinical hit-to-lead optimization and protein-conformation analysis.
  • Internal drug development and collaboration with pharmaceutical discovery teams.

Key facts

  • $47M Series A announced April 27, 2026; updated to $55M total Series A financing in May, not $47M plus $55M.
  • November 6, 2026 Kos BioVentures announcement identifies participation in the earlier financing; individual cheque undisclosed.
  • Sutter Hill Ventures led; Lilly Ventures, Chemistry, Alexandria Venture Investments, NY Ventures and Kos among disclosed participants.
  • Preclinical Microcosmos combines protein dynamics simulations and AI with wet-lab experiments; no disclosed human efficacy outcome.
  • 12 discovery partnerships reported in BIO 2026 issuer profile; partner contract economics and valuation undisclosed.

Funding history (newest first)

Series A (cumulative; original $47M announced April 27, expanded to $55M by May)

2026-05 $55M Valuation: Undisclosed
  • Sutter Hill Ventures (lead)
  • Lilly Ventures (participant)
  • Chemistry (participant)
  • Alexandria Venture Investments (participant)
  • Empire State Development NY Ventures (participant)
  • Kos BioVentures (Kos Biotechnology Partners) (participant)

Source: Read source · prnewswire.com

Competitive landscape

Edge: Team includes molecular simulation scientists associated with Anton supercomputer development; differentiated thesis emphasizes time-dependent protein motion with physics-guided training signals versus static binding structures. Performance claims and six-week design examples come from the company, without controlled clinical or commercial validation.

  • Schrödinger direct

    Physics-based computational chemistry plus proprietary drug pipeline; more established integrated software and therapeutics model.

  • Relay Therapeutics adjacent

    Protein-motion-informed drug discovery with clinical programs; a comparable philosophy but different assets and validations.

  • QSimulate direct

    Quantum-mechanical simulation tools for drug discovery; comparison requires validation on the same molecular targets.

  • Iktos adjacent

    AI-guided small-molecule design with different balance of generative chemistry and physics.

Market / IPO context

Editorial / static context — not a live quote.

FAQs about Fathom Therapeutics

Practical answers founders, operators, and investors typically search for.

No. The company said on October 29 that its $55M Series A was financed in May 2026; the November 6 release disclosed Kos BioVentures as a participant in that same earlier round.
The original April 27 company release reported $47M. The later company release describes $55M in total Series A financing in May. It did not disclose the precise additional financing closing date or terms, so the two figures are not separate amounts to sum.
The company has described preclinical candidates and animal studies, but no platform-derived approved therapy or independently verified clinical efficacy outcome was established in the cited releases.

By Venture Capital Tracker

Last updated:

Editorial note: AI tools assisted with research, structure, or drafting. Venture Capital Tracker retains human editorial responsibility for factual accuracy, relevance, and source quality before publication.