VC fund profile · evidence-aware directory data
Two Sigma Ventures stages, portfolio and investment profile
Venture arm incubated inside quantitative trading firm Two Sigma, backing data-driven startups and AI companies from seed through growth. In May 2026 the team spun out as independent Deviation Capital with ~$2B AUM managing the legacy TSV portfolio.
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Stage-based planning range
$1M–$10M
This is a planning range inferred from stage coverage, not a firm-disclosed check size.
Methodology: Stage bucket inferred from the rounds a fund leads or invests in.
No firm-specific check-size disclosure is recorded.
Investment stages
Leads: Seed, Series A
Participates: Pre-Seed, Seed, Series A, Series B+
Sector focus
ai-ml · deep-tech
Geography
100 Avenue of the Americas, New York, NY 10013
Founded 2012
Fund size / AUM
Not recorded
A separate fund-size evidence record is not yet available.
Portfolio in our directory
7
Linked startup profiles
Latest fund vehicle
Not recorded
Vehicle name, size, and vintage are not yet structured.
Recent tracked investment
Not recorded
No dated round explicitly links this fund.
Rounds they lead
Rounds they invest
Last verified: Not recorded. Check-size evidence is labeled by basis so planning estimates are not presented as firm disclosures.
Portfolio companies we track
Startups in our directory that list Two Sigma Ventures as an investor (7 total).
- Aradigm Benefits platform enabling sustainable employer access to cell and gene therapies.
- Arda Therapeutics Targeted cell-depletion therapies for chronic diseases using oncology modalities outside cancer.
- Distributional AI evaluation platform measuring production ML model quality, drift, and reliability.
- Insitro ML-driven drug discovery platform applying large-scale biology data to identify novel therapeutics.
- Osmo AI-powered digital olfaction — fragrance design via molecular data and machine learning.
- Recursion Techbio company using automated labs and ML for drug discovery at scale.
- Rive Real-time interactive animation platform and runtime for apps, games, and embedded UIs.
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