Frist Cressey Ventures

Nashville healthcare venture firm co-founded in 2016 by former U.S. Senate Majority Leader Bill Frist, MD and Bryan Cressey. Backs early-stage companies transforming care delivery with technology and tech-enabled services, including AI-native models. Closed oversubscribed Fund IV at $425M (Feb 2026 PR), bringing firm AUM toward ~$1B. Strategic LP network includes The Cigna Group, MedStar Health, and OhioHealth. HQ at 40 Burton Hills Blvd, Nashville, TN.

Typical check size

$1M-$10M (stage-based estimate)

Founded

2016

Headquarters

Nashville, TN

AUM

Fund IV $425M; ~$1B firm AUM (Feb 2026 PR)

Rounds they lead

Seed Series A Series B

Rounds they invest

Seed Series A Series B Growth

Portfolio companies we track

Startups in our directory that list Frist Cressey Ventures as an investor (2 total).

FAQs about Frist Cressey Ventures

Stage fit, check size, thesis, and how founders typically approach this firm — based on public sources and our directory.

Nashville, Tennessee (40 Burton Hills Blvd); the firm also has Chicago roots via co-founder Bryan Cressey.

Bill Frist, MD and Bryan Cressey founded the firm in 2016.

Oversubscribed $425M Fund IV closed February 2026 (fcventures.com / PR Newswire), focused on early-stage care-delivery and AI-native healthcare.

Early-stage healthcare — typically seed through Series B, with selective growth follow-ons; confirm current mandate with the firm.

Healthcare services, health IT, and tech-enabled care delivery — not classic drug discovery.

Yes — known to lead and incubate healthcare companies (e.g., Monogram Health).

Via fcventures.com and warm intros through Nashville/Chicago healthcare operators and strategic LPs.

Fund IV $425M; firm materials cite nearly $1B AUM after the Fund IV close (Feb 2026) — verify on ADV for regulatory AUM.

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