Investor profile for First Avenue Ventures: stage-based planning range, investment stages, sector focus, portfolio companies, sources, and verification status. Part of the Venture Capital Tracker directory.
First Avenue Ventures
stages, portfolio and investment profile
Birmingham early-stage firm with a Life Science Fund I focused on UAB/Birmingham life sciences and an Opportunity Fund for seed and pre-seed companies; Opportunity Fund commitments exceeded $2M as of April 2024, with typical Opportunity Fund checks of $100k–$500k.
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Stage fit, check size, thesis, and how founders typically approach this firm — based on public sources and our directory.
Per our directory, First Avenue leads pre-seed and seed rounds and may participate through Series A. The firm runs a Life Science Fund I tied to UAB/Birmingham life sciences plus an Opportunity Fund aimed at seed and pre-seed companies.
Public materials for the Opportunity Fund cite checks of roughly $100k–$500k. Life Science Fund I sizing is not published as a single fixed amount; founders should confirm current terms with the firm rather than assuming one check for every deal.
First Avenue is based in Birmingham, AL. Life Science Fund I emphasizes UAB and Birmingham life-sciences deal flow; Opportunity Fund activity can include broader early-stage companies—founders should ask the firm about geography fit for a specific thesis.
Our directory tags biotech/life sciences, healthtech, and enterprise SaaS. The Life Science Fund I is oriented to Birmingham/UAB life sciences; the Opportunity Fund covers seed and pre-seed opportunities across the firm's broader early-stage mandate.
Our directory marks First Avenue as a pre-seed and seed lead. At Series A it more often participates alongside other institutional investors rather than always writing the lead check.
As of April 2024, public reporting noted Opportunity Fund commitments exceeding $2M. We do not list a firm-wide AUM figure because a single verified total across all vehicles is not available in our sources.
Start at firstavenueventures.com and clarify whether Life Science Fund I or the Opportunity Fund is the better fit. Warm intros from Birmingham operators, UAB-affiliated founders, or local angels help; be ready with stage, sector, and capital needs that match the $100k–$500k Opportunity Fund range when relevant.
We do not yet have a dedicated First Avenue Ventures article. For Birmingham early-stage context, see our city and industry hubs covering healthtech and biotech/life sciences, and watch for future Alabama investor coverage.
Editorial note: AI tools assisted with research, structure, or drafting. Venture Capital Tracker retains human editorial responsibility for factual accuracy, relevance, and source quality before publication.